1-ethyl-2-[5-[1-[6-[[3-[[3-[3-[1-[(2R,5R)-4-hydroxy-5-[[hydroxy-[hydroxy(phosphonooxy)phosphoryl]oxyphosphoryl]oxymethyl]oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]prop-2-ynylamino]-3-oxopropyl]disulfanyl]-1-[[6-[3-[1-[(2R,5R)-4-hydroxy-5-(phosphonooxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]propylamino]-6-oxohexyl]amino]-1-oxopropan-2-yl]amino]-6-oxohexyl]-3,3-dimethyl-5-sulfoindol-1-ium-2-yl]penta-2,4-dienylidene]-3,3-dimethylindole-5-sulfonic acid

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘧啶核苷酸
• 英文名称: 1-ethyl-2-[5-[1-[6-[[3-[[3-[3-[1-[(2R,5R)-4-hydroxy-5-[[hydroxy-[hydroxy(phosphonooxy)phosphoryl]oxyphosphoryl]oxymethyl]oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]prop-2-ynylamino]-3-oxopropyl]disulfanyl]-1-[[6-[3-[1-[(2R,5R)-4-hydroxy-5-(phosphonooxymethyl)oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]propylamino]-6-oxohexyl]amino]-1-oxopropan-2-yl]amino]-6-oxohexyl]-3,3-dimethyl-5-sulfoindol-1-ium-2-yl]penta-2,4-dienylidene]-3,3-dimethylindole-5-sulfonic acid
• 化学式: C69H95N10O32P4S4+
• 分子量: 1828.7
• InChiKey: ZKVCLTATEWJIMF-LYQKKFJRSA-O

计算性质

• 辛醇/水分配系数(LogP)：
  -3.7
• 重原子数：
  119
• 可旋转键数：
  44
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.52
• 拓扑面积：
  683
• 氢给体数：
  16
• 氢受体数：
  35

文献信息

• Methods and compositions for sequencing a nucleic acid
  申请人：Siddiqi M. Suhaib

  公开号：US20070190546A1

  公开（公告）日：2007-08-16

  The invention provides a family of nucleotide analogs useful in sequencing nucleic acids containing a homopolymer region comprising, for example, two or more base repeats, and to sequencing methods using such nucleotide analogs.