6-亚硝基苯并(a)芘 | 118745-15-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 芘
• 中文名称: 6-亚硝基苯并(a)芘
• 英文名称: 6-Nitrosobenzo(a)pyrene
• 英文别名: 6-nitrosobenzo[a]pyrene
• CAS: 118745-15-6
• 化学式: C₂₀H₁₁NO
• 分子量: 281.3
• InChiKey: ICRDTHCKNWXAFG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  22
• 可旋转键数：
  0
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  29.4
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] ANTIFUNGAL COMPOSITIONS<br/>[FR] COMPOSITIONS ANTIFONGIQUES
  申请人：ACHILLION PHARMACEUTICALS INC

  公开号：WO2003055448A2

  公开（公告）日：2003-07-10

  Methods for elucidating an antifungal or anti-yeast compound which selectively bind to a fungal or yeast zinc finger-containing protein within a fungus are disclosed. Assays of screening for compounds that are effective for binding to a fungal or yeast zinc ginger-containing protein are also provided. It is also provided a pharmaceutical composition containing an effective amount of a compound or compounds identified as effective for binding to or associating with a fungal or yeast zinc finger-containing protein using the disclosed methods. Fungal and/or yeast infections can be treated or prevented by administering to a patient in need of treatment the pharmaceutical composition containing an effective amount of an compound or compounds identified as effective for binding to or associating with a fungal or yeast zinc finger-containing protein using the disclosed methods.