2-[5-[1-ethyl-3,3-dimethyl-5-(trioxidanylsulfanyl)indol-2-ylidene]penta-1,3-dienyl]-1-[3-[[3-[3-[1-[(2R,4R,5R)-4-hydroxy-5-[[hydroxy-[hydroxy(phosphonooxy)phosphoryl]oxyphosphoryl]oxymethyl]oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]prop-2-ynylamino]-3-oxopropyl]disulfanyl]propyl]-3,3-dimethylindol-1-ium-5-sulfonic acid

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘧啶核苷酸
• 英文名称: 2-[5-[1-ethyl-3,3-dimethyl-5-(trioxidanylsulfanyl)indol-2-ylidene]penta-1,3-dienyl]-1-[3-[[3-[3-[1-[(2R,4R,5R)-4-hydroxy-5-[[hydroxy-[hydroxy(phosphonooxy)phosphoryl]oxyphosphoryl]oxymethyl]oxolan-2-yl]-2,4-dioxopyrimidin-5-yl]prop-2-ynylamino]-3-oxopropyl]disulfanyl]propyl]-3,3-dimethylindol-1-ium-5-sulfonic acid
• 化学式: C45H57N5O21P3S4+
• 分子量: 1225.1
• InChiKey: FXUPXYRVKVNQJE-GZEQTDTESA-O

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  78
• 可旋转键数：
  26
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  451
• 氢给体数：
  9
• 氢受体数：
  25

文献信息

• Methods And Compositions For Sequencing A Nucleic Acid
  申请人：Siddiqi Suhaib

  公开号：US20080227970A1

  公开（公告）日：2008-09-18

  The invention provides a family of tethered nucleotide analogs useful in sequencing nucleic acids containing a homopolymer region comprising, for example, two or more base repeats, and to sequencing methods using such tethered nucleotide analogs.
• US7994304B2
  申请人：——

  公开号：US7994304B2

  公开（公告）日：2011-08-09