6-氨基-1H-苯并咪唑-4-醇 | 100868-28-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 中文名称: 6-氨基-1H-苯并咪唑-4-醇
• 英文名称: 6-Amino-4-hydroxy-benzimidazol
• 英文别名: 6-amino-1(3)H-benzoimidazol-4-ol；6-amino-1(3)H-benzimidazol-4-ol；6-amino-1H-benzo[d]imidazol-4-ol；6-amino-1H-benzimidazol-4-ol
• CAS: 100868-28-8
• 化学式: C₇H₇N₃O
• mdl: MFCD19204895
• 分子量: 149.152
• InChiKey: FQHVHGPRGZYIFI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  74.9
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 乙醇 、 钯 作用下， 生成 6-氨基-1H-苯并咪唑-4-醇
  参考文献：
  名称：

  Benzimidazoles and Benzotraizoles as Growth Antagonists

  摘要：

  DOI：

  10.1021/ja01642a051

文献信息

• Kit for assaying saccharified protein
  申请人：——

  公开号：US20030226769A1

  公开（公告）日：2003-12-11

  A novel method of assaying glycated hemoglobin, glycated albumin or a fructosamine which is a degradation product thereof are disclosed. In particular, the present invention provides a method for assaying fructosamine which comprises oxidizing fructosamine by using a compound having an imidazole group as a catalyst in the presence of an appropriate mediator (an electron acceptor), and measuring the reduced form of the mediator.

  本发明公开了一种测定糖化血红蛋白、糖化白蛋白或其降解产物果糖胺的新方法。特别是，本发明提供了一种果糖胺的检测方法，该方法包括在适当的介质（电子受体）存在下，使用具有咪唑基团的化合物作为催化剂氧化果糖胺，并测量介质的还原形式。
• EXTERNAL GRADIENT CHROMATOFOCUSING
  申请人：Cryobiophysica, Inc.

  公开号：EP1628729A2

  公开（公告）日：2006-03-01
• External gradient chromatofocusing
  申请人：Tsonev I. Latchezar

  公开号：US20070144973A1

  公开（公告）日：2007-06-28

  The invention provides novel methods for the separation of charged molecules such as proteins according to the isoelectric points (pI's) and includes the systems and buffering compositions employed for isolating charged molecules. The invention further provides for modifications to the above described chromatographic methods that enable the separation of charged molecules exhibiting virtually identical pI's by shifting both the buffer's pKa and the pI's of the eluted charged molecules while they are traversing the ion exchange column.
• US7790025B2
  申请人：——

  公开号：US7790025B2

  公开（公告）日：2010-09-07
• [EN] EXTERNAL GRADIENT CHROMATOFOCUSING<br/>[FR] CHROMATOFOCALISATION A GRADIENT EXTERNE
  申请人：DNAVAX INC

  公开号：WO2004103519A2

  公开（公告）日：2004-12-02

  The invention provides novel methods for the separation of charged molecules such a proteins according to their isoelectric points (pI's) and includes the systems and buffering compositions employed for isolating charged molecules. The invention further provides for modifications to the above described chromatographic methods that enable the separation of charged molecules exhibiting virtually identical pl's by shifting both the buffer's pKa and the pl's of the eluted charged molecules while they are traversing the ion exchange column.