Cytotoxin-targeting molecule conjugates comprising cytotoxin and an antibody, growth factor, or polysaccharide together with a pH-sensitive or redox potential-sensitive linker. Novel ansamitocins and recombinant genes and organisms that produce them. The use of the described conjugates in the treatment of cancer and other hyperproliferation diseases.
METHOD FOR PRODUCING AND STORING LIQUID COMPOSITION COMPRISING TETRAHYDRO-4H-1,3,5-OXADIAZINE-4-ONE
申请人:Kao Corporation
公开号:EP2915807B1
公开(公告)日:2017-10-11
METHODS OF TREATING TRAUMATIC BRAIN INJURY
申请人:OXEIA BIOPHARMACEUTICALS, INC.
公开号:US20170266257A1
公开(公告)日:2017-09-21
The present disclosure provides methods for treating traumatic brain injury and other neurological disorders in a subject in need thereof, comprising administering to the subject an effective amount of a composition comprising ghrelin or a ghrelin variant. This invention provides for methods for treating a severe or moderate traumatic brain injury in a patient wherein said method comprises administering to the subject suffering from said severe or moderate traumatic brain injury a therapeutic effective amount of ghrelin or a ghrelin variant or a composition comprising ghrelin or a ghrelin variant so as to treat said severe or moderate traumatic brain injury.
CD3/CD38 T CELL RETARGETING HETERO-DIMERIC IMMUNOGLOBULINS AND METHODS OF THEIR PRODUCTION
申请人:GLENMARK PHARMACEUTICALS S.A.
公开号:US20190135918A1
公开(公告)日:2019-05-09
The present invention relates to hetero-dimeric immunoglobulins that target both a component of the human CD3 antigen and a component of the human CD38 antigen and methods of making the same. The present invention also relates to antibodies which bind to the human CD38 antigen and derivatives thereof for use as therapeutic or diagnostic reagents and methods of making the same.
[EN] HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING SAME<br/>[FR] COMPOSÉ HÉTÉROCYCLIQUE ET DISPOSITIF ÉLECTROLUMINESCENT ORGANIQUE UTILISANT CE COMPOSÉ<br/>[KO] 헤테로고리 화합물 및 이를 이용한 유기발광소자