COMPOSITIONS AND METHODS FOR PRODUCING POLYPEPTIDES WITH A MODIFIED GLYCOSYLATION PATTERN IN PLANT CELLS
申请人:Yissum Research and Development Company of the
Hebrew University of Jerusalem Ltd.
公开号:EP3221455A2
公开(公告)日:2017-09-27
[EN] COMPOSITIONS AND METHODS FOR PRODUCING POLYPEPTIDES WITH A MODIFIED GLYCOSYLATION PATTERN IN PLANT CELLS<br/>[FR] COMPOSITIONS ET PROCÉDÉS DE PRODUCTION DE POLYPEPTIDES PRÉSENTANT UN SCHÉMA DE GLYCOSYLATION MODIFIÉ DANS DES CELLULES VÉGÉTALES
申请人:YISSUM RES DEV CO
公开号:WO2016079739A2
公开(公告)日:2016-05-26
A method of modifying a glycosylation pattern of a polypeptide-of-interest in a plant or plant cell is provided. The method comprising expressing in a plant or plant cell transformed to express at least one glycosidase in a subcellular compartment, a nucleic acid sequence encoding the polypeptide-of-interest, such that the at least one glycosidase and the polypeptide-of-interest are co-localized to the subcellular compartment of the plant or plant cell, thereby modifying the glycosylation pattern of the polypeptide-of-interest in the plant or plant cell.