1-(4-(4-p-tolylphthalazin-1-yl)piperazin-1-yl)ethanone

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 1-(4-(4-p-tolylphthalazin-1-yl)piperazin-1-yl)ethanone
• 英文别名: 1-{4-[4-(4-Methylphenyl)phthalazin-1-yl]piperazin-1-yl}ethanone；1-[4-[4-(4-methylphenyl)phthalazin-1-yl]piperazin-1-yl]ethanone
• 化学式: C₂₁H₂₂N₄O
• 分子量: 346.432
• InChiKey: AVWJDVDAQMDRFS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  26
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  49.3
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• [EN] PHENYL PHTHALAZINE DERIVATIVE, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME<br/>[FR] DÉRIVÉ DE PHÉNYLPHTALAZINE, SA MÉTHODE DE PRÉPARATION ET COMPOSITION PHARMACEUTIQUE LE COMPRENANT
  申请人：DAE WOONG PHARMA

  公开号：WO2018080216A1

  公开（公告）日：2018-05-03

  The present invention relates to a compound represented by Chemical Formula 1, or a pharmaceutically acceptable salt thereof. The compound according to the present invention can be usefully used for the prevention or treatment of cardiovascular diseases.

  本发明涉及化学式1所代表的化合物，或其药用可接受的盐。根据本发明的化合物可用于预防或治疗心血管疾病。
• Phenyl phthalazine derivative, method for the preparation thereof, and pharmaceutical composition comprising the same
  申请人：Seoul National University Hospital

  公开号：US10947241B2

  公开（公告）日：2021-03-16

  The present invention relates to a compound represented by Chemical Formula 1, or a pharmaceutically acceptable salt thereof. The compound according to the present invention can be usefully used for the prevention or treatment of cardiovascular diseases.

  本发明涉及一种由化学式 1 表示的化合物或其药学上可接受的盐。本发明的化合物可用于预防或治疗心血管疾病。
• PHENYL PHTHALAZINE DERIVATIVE, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
  申请人：Seoul National University Hospital

  公开号：US20190241574A1

  公开（公告）日：2019-08-08

  The present invention relates to a compound represented by Chemical Formula 1, or a pharmaceutically acceptable salt thereof. The compound according to the present invention can be usefully used for the prevention or treatment of cardiovascular diseases.