2,6-difluoro-N-[(6-phenylsulfanylpyridazin-3-yl)carbamoyl]benzamide | 1173149-91-1

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 2,6-difluoro-N-[(6-phenylsulfanylpyridazin-3-yl)carbamoyl]benzamide
• CAS: 1173149-91-1
• 化学式: C₁₈H₁₂F₂N₄O₂S
• 分子量: 386.382
• InChiKey: TUPDOWTWYWBYFB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  27
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  109
• 氢给体数：
  2
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  3-氨基-6-(苯硫基)哒嗪 、 2,6-二氟苯甲酰异氰酸酯 以 二氯甲烷 为溶剂， 以84%的产率得到2,6-difluoro-N-[(6-phenylsulfanylpyridazin-3-yl)carbamoyl]benzamide
  参考文献：
  名称：

  Design, Synthesis, and Bioactivity Study of Novel Benzoylpyridazyl Ureas

  摘要：

  A series of novel benzoylpyridazyl ureas were designed and synthesized from maleic anhydride and hydrazine monohydrate. These benzoylureas were identified by H-1 NMR spectroscopy and element analysis. The bioactivities of the new compounds were evaluated. These compounds exhibited larvicidal activities against oriental armyworm, and in particular, compound 13 displayed comparable activity to the commercial insecticide Hexaflumuron. Most of these compounds also had some larvicidal activities against mosquito. Interestingly, some compounds showed good plant growth regulatory activities.

  DOI：

  10.1021/jf900882c

文献信息

• Design, Synthesis, and Bioactivity Study of Novel Benzoylpyridazyl Ureas
  作者：Ranfeng Sun、Yonglin Zhang、Fuchun Bi、Qingmin Wang

  DOI：10.1021/jf900882c

  日期：2009.7.22

  A series of novel benzoylpyridazyl ureas were designed and synthesized from maleic anhydride and hydrazine monohydrate. These benzoylureas were identified by H-1 NMR spectroscopy and element analysis. The bioactivities of the new compounds were evaluated. These compounds exhibited larvicidal activities against oriental armyworm, and in particular, compound 13 displayed comparable activity to the commercial insecticide Hexaflumuron. Most of these compounds also had some larvicidal activities against mosquito. Interestingly, some compounds showed good plant growth regulatory activities.