4-Pyrimidinecarboxylic acid, 1,6-dihydro-5-fluoro-6-oxo-2-phenyl-, ethyl ester | 143329-00-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 4-Pyrimidinecarboxylic acid, 1,6-dihydro-5-fluoro-6-oxo-2-phenyl-, ethyl ester
• 英文别名: ethyl 5-fluoro-6-oxo-2-phenyl-1H-pyrimidine-4-carboxylate
• CAS: 143329-00-4
• 化学式: C₁₃H₁₁FN₂O₃
• 分子量: 262.24
• InChiKey: WTIXZUKEKNWPLM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  67.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• PYRIMIDINONE COMPOUNDS AND METHODS FOR PREVENTING AND TREATING INFLUENZA
  申请人：Webb Thomas R.

  公开号：US20140079666A1

  公开（公告）日：2014-03-20

  In one aspect, the invention relates to novel, broad-spectrum anti-viral, pyrimidinone compounds, methods of use, compositions and kits useful in treating and/or preventing influenza. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.