1-Benzyl-5,5-bis(2-pyridin-4-ylethyl)-1,3-diazinane-2,4,6-trione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 1-Benzyl-5,5-bis(2-pyridin-4-ylethyl)-1,3-diazinane-2,4,6-trione
• 化学式: C₂₅H₂₄N₄O₃
• 分子量: 428.5
• InChiKey: JHXXKVWFWGWYSN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  32
• 可旋转键数：
  8
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  92.3
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Use of bispyridines to improve labeling of nucleophiles
  申请人：Agilent Technologies, Inc.

  公开号：US11092595B2

  公开（公告）日：2021-08-17

  Bispyridines improve the labeling of nucleophiles, including amines and thiols and are particularly useful for improving labeling with acidic and basic labels. Use of bispyridines with such labels dramatically increases labeling compared to protocols without a bispyridine. The labeled nucleophile can then be subjected to standard analytical methods.

  双吡啶可以改善包括胺和硫醇在内的亲核物的标记效果，尤其适用于改善酸性和碱性标记的标记效果。与不使用双吡啶的方案相比，使用双吡啶与此类标签可显著提高标记效果。标记后的亲核物可用于标准分析方法。
• USE OF BISPYRIDINES TO IMPROVE LABELING OF NUCLEOPHILES
  申请人：ProZyme, Inc.

  公开号：US20190041384A1

  公开（公告）日：2019-02-07

  Bispyridines improve the labeling of nucleophiles, including amines and thiols and are particularly useful for improving labeling with acidic and basic labels. Use of bispyridines with such labels dramatically increases labeling compared to protocols without a bispyridine. The labeled nucleophile can then be subjected to standard analytical methods.
• Kits for Using Bispyridines to Improve Labeling of Nucleophiles
  申请人：Agilent Technologies, Inc.

  公开号：US20210333269A1

  公开（公告）日：2021-10-28

  Bispyridines improve the labeling of nucleophiles, including amines and thiols and are particularly useful for improving labeling with acidic and basic labels. Use of bispyridines with such labels dramatically increases labeling compared to protocols without a bispyridine. The labeled nucleophile can then be subjected to standard analytical methods.