4-methoxy-4'-vinylbenzophenone | 24993-90-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-methoxy-4'-vinylbenzophenone
• 英文别名: 4-(-p-Methoxybenzoyl)-styrol；4-Methoxy-4'-vinylbenzophenon；4-methoxyphenyl 4-vinylphenyl methanone；(4-Ethenylphenyl)-(4-methoxyphenyl)methanone
• CAS: 24993-90-6
• 化学式: C₁₆H₁₄O₂
• 分子量: 238.286
• InChiKey: XYCITMXYSRJMAX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  甲基丙烯酸烯丙酯 、 4-methoxy-4'-vinylbenzophenone 在 dihydrogen hexachloroplatinate 作用下， 生成
  参考文献：
  名称：

  CHROMENE COMPOUND

  摘要：

  公开号：

  EP2684886B1
• 作为产物：
  描述：

  4-β-Bromethyl-4'-methoxybenzophenon 以93%的产率得到
  参考文献：
  名称：

  POGOSYAN G. M., XIMIYA NEPREDELNYX SOEDIN., (EREVAN), 1979, HO 1, 159-179

  摘要：

  DOI：

文献信息

• Carbonylative Suzuki Coupling Reaction Catalyzed by a Hydrospirophosphorane Palladium Complex
  作者：Przemysław Wójcik、Labrini Sygellou、Andrzej Gniewek、Anna Skarżyńska、Anna Trzeciak

  DOI：10.1002/cctc.201700946

  日期：2017.12.8

  A Pd complex with the H‐spirophosphorane ligand, PdCl2P(OCMe2CMe2O)OC6H4NH2} (Cat. 1), was used as the catalyst in the carbonylative Suzuki coupling of substituted iodobenzenes with arylboronic acids and with sodium tetraphenylborate. Substituted diarylketones were obtained in good to excellent yields and a selectivity over 95 % under 1 atm of CO with 1.5 mol % of the catalyst. The promoting role

  在取代的碘代苯与芳基硼酸的羰基化铃木偶联反应中，使用具有H-螺磷烷配体PdCl 2 P（OCMe 2 CMe 2 O）OC 6 H 4 NH 2 } （类别1）的Pd络合物作为催化剂。和四苯硼酸钠。得到的二芳基酮的收率好至极好，在1大气压的CO和1.5摩尔％的催化剂下，选择性超过95％。证明了H-螺膦基配体在催化过程中的促进作用。我们使用了X射线光电子能谱，TEM和31P NMR光谱揭示反应期间。图1的化合物经历转变成具有螺磷膦烷配体或通过其脱烷基作用形成的其他P配体的Pd络合物，并转变成Pd纳米颗粒。所有这些Pd种类都有助于提高系统的生产率。
• A General Synthesis of Diarylketones by Means of a Three-Component Cross-Coupling of Aryl and Heteroaryl Bromides, Carbon Monoxide, and Boronic acids
  作者：Helfried Neumann、Anne Brennführer、Matthias Beller

  DOI：10.1002/chem.200800001

  日期：2008.4.18

  Pd(OAc)2/di-1-adamantyl-n-butylphosphine (cataCXium A) is highly active in the three-component Suzuki carbonylation and represents the most general catalyst system reported up to now. A broad range of aryl/heteroaryl bromides and aryl boronic acids can be coupled to the corresponding diarylketones at low catalyst loadings.

  Pd（OAc）2 /二-1-金刚烷基-正丁基膦（cataCXium A）在三组分铃木羰基化反应中具有很高的活性，是迄今为止报道的最通用的催化剂体系。各种各样的芳基/杂芳基溴化物和芳基硼​​酸可以在低催化剂负载下与相应的二芳基酮偶联。
• An Efficient and Practical Sequential One-Pot Synthesis of Suprofen, Ketoprofen and Other 2-Arylpropionic Acids
  作者：Helfried Neumann、Anne Brennführer、Matthias Beller

  DOI：10.1002/adsc.200800415

  日期：2008.10.6

  A novel sequential double carbonylation to synthesize anti-inflammatory drugs such as Ketoprofen and Suprofen has been developed. Starting from easily available aryl halides and arylboronic acids a one-pot carbonylative Suzuki and hydroxycarbonylation reaction sequence proceeds in good selectivity and high yield in the presence of the palladium/cataCXium® A catalyst system. Applying optimized conditions

  已经开发出新颖的连续双羰基化来合成抗炎药，例如酮洛芬和Suprofen。从容易获得的芳基卤化物和芳基硼酸开始在良好的选择性，并在钯/ CATA的存在下高收率一锅carbonylative铃木和羟基羰基化反应进行序列CX鎓®的催化剂体系。在优化条件下，以高收率合成了不同的2-芳基丙酸。
• SYNTHETIC COMPOSITION AND COATING FOR CELL CULTURE
  申请人：Henry David

  公开号：US20120282697A1

  公开（公告）日：2012-11-08

  A composition for forming a polymeric cell culture surface includes (i) a pre-polymer comprising a polymer backbone, a cationic moiety conjugated to the backbone, and a cross-linker moiety conjugated to the backbone; and (ii) a peptide-polymer comprising a polymer backbone and cell adhesive peptide conjugated to the backbone. Cross-linked coatings for cell culture that have a suitable amount of cell adhesive peptide and cationic moiety may be formed from the pre-polymer and peptide-polymer.

  一种用于形成聚合细胞培养表面的组合物包括（i）预聚合物，其包括聚合物骨架，与骨架共轭的阳离子基团和与骨架共轭的交联剂基团；和（ii）肽聚合物，其包括聚合物骨架和细胞黏附肽共轭到骨架上。预聚合物和肽聚合物可以形成适量细胞黏附肽和阳离子基团的交联涂层，用于细胞培养。
• ORGANOPOLYSILOXANE GRAFT POLYMER
  申请人：Kao Corporation

  公开号：EP2927253A1

  公开（公告）日：2015-10-07

  The present invention relates to an organopolysiloxane graft polymer including an organopolysiloxane segment as a main chain thereof and an unsaturated monomer-derived polymer segment as a side chain thereof, in which a content of the organopolysiloxane segment in the organopolysiloxane graft polymer is not less than 35% by mass and not more than 70% by mass, and the unsaturated monomer-derived polymer segment contains a repeating unit derived from a nonionic unsaturated monomer having a glass transition temperature Tg of 60°C or higher (except for a repeating unit derived from an unsaturated monomer containing an amino group) in an amount of not less than 40% by mass and not more than 90% by mass, and further contains a repeating unit derived from a cationic unsaturated monomer in an amount of not less than 10% by mass and not more than 60% by mass.

  本发明涉及一种有机聚硅氧烷接枝聚合物，包括作为其主链的有机聚硅氧烷段和作为其侧链的不饱和单体衍生聚合物段，其中有机聚硅氧烷段在有机聚硅氧烷接枝聚合物中的含量不低于35%（质量百分比）且不超过70%（质量百分比）、不饱和单体衍生的聚合物段含有由玻璃化转变温度 Tg 为 60°C 或更高的非离子不饱和单体衍生的重复单元（由含有氨基的不饱和单体衍生的重复单元除外），其含量不低于 40%（按质量计）且不超过 90%（按质量计），还含有由阳离子不饱和单体衍生的重复单元，其含量不低于 10%（按质量计）且不超过 60%（按质量计）。