3-Hexyl-4-methyl-1,3-oxazolidin-2-one | 1346645-76-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 英文名称: 3-Hexyl-4-methyl-1,3-oxazolidin-2-one
• 英文别名: 3-hexyl-4-methyl-1,3-oxazolidin-2-one
• CAS: 1346645-76-8
• 化学式: C₁₀H₁₉NO₂
• 分子量: 185.266
• InChiKey: DRBXHNNVLGIKQX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  二氧化碳 、 1-hexyl-2-methylaziridine 在 1,5-二氮杂双环[4.3.0]壬-5-烯 、 lithium iodide 作用下， 以 甲苯 为溶剂， 反应 5.0h， 生成 3-Hexyl-4-methyl-1,3-oxazolidin-2-one 、 3-Hexyl-5-methyl-1,3-oxazolidin-2-one
  参考文献：
  名称：

  Organocatalyzed cycloaddition of carbon dioxide to aziridines

  摘要：

  An efficient and simple process for the fixation of carbon dioxide (CO2) to aziridine for the synthesis of 2-oxazolidinone by using DBN as catalyst, Lil as an additive under atmospheric pressure was developed. This chemical fixation of CO2 could also be carried out at room temperature with prolonged reaction time. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2011.09.092

文献信息

• Organocatalyzed cycloaddition of carbon dioxide to aziridines
  作者：Yichen Wu、Guosheng Liu

  DOI：10.1016/j.tetlet.2011.09.092

  日期：2011.11

  An efficient and simple process for the fixation of carbon dioxide (CO2) to aziridine for the synthesis of 2-oxazolidinone by using DBN as catalyst, Lil as an additive under atmospheric pressure was developed. This chemical fixation of CO2 could also be carried out at room temperature with prolonged reaction time. (C) 2011 Elsevier Ltd. All rights reserved.