1-Allyloxy-3-diphenylamino-propan-2-ol | 82073-87-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1-Allyloxy-3-diphenylamino-propan-2-ol
• 英文别名: 1-(Diphenylamino)-3-[(prop-2-en-1-yl)oxy]propan-2-ol；1-(N-phenylanilino)-3-prop-2-enoxypropan-2-ol
• CAS: 82073-87-8
• 化学式: C₁₈H₂₁NO₂
• 分子量: 283.37
• InChiKey: ZSWMFKSJLVBWOC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  21
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  32.7
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  烯丙基缩水甘油醚 、 二苯胺 在 aluminium(III) triflate 作用下， 以 甲苯 为溶剂， 反应 24.0h， 以57%的产率得到1-Allyloxy-3-diphenylamino-propan-2-ol
  参考文献：
  名称：

  Aluminium triflate: an efficient recyclable Lewis acid catalyst for the aminolysis of epoxides

  摘要：

  Epoxides are powerful starting materials for a range of useful materials and can be converted into, amongst others, amino alcohols. In this work, a range of epoxides was ring-opened using various alkyl- and arylamines under the action of aluminium triflate as a catalyst. This catalyst was found to be highly active, producing the desired amino alcohol products in high yields with low catalyst loadings. Additionally, it was shown that the aluminium triflate catalyst is recyclable by simple extraction into water and may be re-used several times. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.07.036

文献信息

• Aluminium triflate: an efficient recyclable Lewis acid catalyst for the aminolysis of epoxides
  作者：D. Bradley G. Williams、Michelle Lawton

  DOI：10.1016/j.tetlet.2006.07.036

  日期：2006.9

  Epoxides are powerful starting materials for a range of useful materials and can be converted into, amongst others, amino alcohols. In this work, a range of epoxides was ring-opened using various alkyl- and arylamines under the action of aluminium triflate as a catalyst. This catalyst was found to be highly active, producing the desired amino alcohol products in high yields with low catalyst loadings. Additionally, it was shown that the aluminium triflate catalyst is recyclable by simple extraction into water and may be re-used several times. (c) 2006 Elsevier Ltd. All rights reserved.