6-甲基-7-氧杂-1-硫杂-4-氮杂螺[4.4]壬烷 | 165261-13-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 唑烷类
• 中文名称: 6-甲基-7-氧杂-1-硫杂-4-氮杂螺[4.4]壬烷
• 英文名称: 6-methyl-7-oxa-1-thia-4-azaspiro[4.4]nonane
• 英文别名: 7-Oxa-1-thia-4-azaspiro[4.4]nonane, 6-methyl-
• CAS: 165261-13-2
• 化学式: C₇H₁₃NOS
• 分子量: 159.252
• InChiKey: OPFPLXAEUOBWQR-UHFFFAOYSA-N

物化性质

• 保留指数：
  2024;2024

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  46.6
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2-甲基四氢呋喃-3-酮 、 半胱胺盐酸盐 在 sodium hydroxide 作用下， 以 水 为溶剂， 生成 6-甲基-7-氧杂-1-硫杂-4-氮杂螺[4.4]壬烷
  参考文献：
  名称：

  Hetero spiro compound as perfuming and flavoring ingredient

  摘要：

  本发明涉及香水和调味品行业。更具体地，它涉及使用6-甲基-7-氧-1-硫-4-氮杂螺[4.4]壬烷，即化学式1作为香料或调味成分。本发明还涉及含有化合物I式作为活性成分的香水或调味消费品或香料或调味组合物。

  公开号：

  US20030175395A1

文献信息

• [EN] COMPOUNDS FOR PROVIDING A LONG-LASTING ODOR<br/>[FR] COMPOSÉS DESTINÉS À FOURNIR UNE ODEUR DE LONGUE DURÉE
  申请人：FIRMENICH & CIE

  公开号：WO2021209396A1

  公开（公告）日：2021-10-21

  The present invention relates to the field of perfumery. More particularly, it relates to compounds of formula (I) that are able to provide a long-lasting or substantive odor to the environment. Moreover, the present invention relates to a method of imparting a long-lasting odor to environment or to surfaces, such as hard surfaces, fabric, skin or hair. Furthermore, the present invention relates to the use of said compounds in perfumery, as well as the perfuming compositions or perfumed articles comprising the invention's compounds.

  本发明涉及香水领域。更具体地说，它涉及能够为环境提供持久或实质性气味的公式（I）化合物。此外，本发明涉及向环境或表面（如硬表面、织物、皮肤或头发）赋予持久气味的方法。此外，本发明涉及所述化合物在香水中的应用，以及包含本发明化合物的香水组合物或香氛制品。
• [EN] ENOL ETHER PROPERFUME<br/>[FR] PRO-PARFUM D'ÉTHER ÉNOLIQUE
  申请人：FIRMENICH & CIE

  公开号：WO2021250164A1

  公开（公告）日：2021-12-16

  The present invention relates to compounds of formula (I) as properfume compounds. In particular, the present invention relates to a method to release a compound being a carbonyl of formula (II), a formate ester of formula (III) and/or an alcohol of formula (IV), by exposing the compound of formula (I) to an environment wherein it is oxidized. Moreover, the present invention relates to a perfuming composition and a perfumed consumer product comprising at least one compound of formula (I).

  本发明涉及作为合适香精化合物的公式(I)的化合物。具体而言，本发明涉及一种释放公式(I)化合物的方法，该方法是通过将公式(I)化合物暴露在氧化环境中，释放出公式(II)的醛基、公式(III)的甲酸酯基和/或公式(IV)的醇基。此外，本发明涉及一种香精组合物和一种含有至少一种公式(I)化合物的香精消费产品。
• [EN] LILY OF THE VALLEY ODORANT<br/>[FR] SUBSTANCE ODORANTE AU PARFUM DE MUGUET
  申请人：FIRMENICH & CIE

  公开号：WO2021069331A1

  公开（公告）日：2021-04-15

  The present invention concerns compound of formula (I) (I) in the form of any one of its stereoisomers or a mixture thereof, and wherein R1 and R2 represent, independently from each other, a hydrogen atom or a C1-2 alkyl group; and -C(Me)2(OMe) group is, relative to position 1, a meta or a para substituent of the aromatic ring or a mixture thereof. The use as a perfuming ingredient of the invention's compound, the invention's compound as part of a perfuming composition or of a perfumed consumer product and a properfume releasing the invention's compound are also part of the present invention.

  本发明涉及化合物的公式(I) (I) 的任一立体异构体或其混合物形式，其中R1和R2分别表示氢原子或C1-2烷基基团；以及相对于位置1，-C(Me)2(OMe)基团是芳香环的间位或对位取代基或其混合物。本发明化合物作为香料成分的用途，本发明化合物作为香料组合物或香水消费品的一部分，以及释放本发明化合物的香水也是本发明的一部分。
• [EN] AMBER ODORANT<br/>[FR] AMBRE ODORANTE
  申请人：FIRMENICH & CIE

  公开号：WO2020239682A1

  公开（公告）日：2020-12-03

  The present invention concerns compound of formula (I) in the form of any one of its stereoisomers or as a mixture thereof, and wherein R1 represents a hydrogen atom, a C1-3 alkyl group or C2-3 alkenyl group; X represents an oxygen atom when R2 represents a C1-4 alkyl group or C2-4 alkenyl group or X represents a CH2-O group when R2 represents a C2-4 alkenyl group or a MeC=O group. The use as a perfuming ingredient of the invention's compound and the invention's compound as part of a perfuming composition or of a perfuming consumer product are also part of the present invention.

  本发明涉及式（I）的化合物，其为其立体异构体之一或其混合物的形式，其中R1代表氢原子、C1-3烷基或C2-3烯基；X代表氧原子，当R2代表C1-4烷基或C2-4烯基时，或X代表CH2-O基团，当R2代表C2-4烯基或MeC=O基团时。本发明的化合物作为香料成分的用途，以及本发明的化合物作为香料组合物或香料消费产品的一部分，也属于本发明的范围。
• [EN] PRO-PERFUME COMPOSITIONS<br/>[FR] COMPOSITIONS DE PROPARFUM
  申请人：FIRMENICH & CIE

  公开号：WO2021123144A1

  公开（公告）日：2021-06-24

  The present invention relates to a perfuming composition comprising at least two properfume compounds selected from the group consisting of a pro-perfume compound releasing a perfume compound upon exposure to light, a pro-perfume compound releasing a perfume compound upon exposure to air/oxygen, a pro-perfume compound releasing a perfume compound upon exposure to heat, a pro-perfume compound releasing a perfume compound upon exposure to moisture and a pro-perfume compound releasing a perfume compound upon exposure to enzymes. The present invention further concerns a perfumed consumer product comprising the inventive perfuming composition, as well as the use of the inventive perfuming composition for improving, enhancing, conferring and/or modifying the fragrance impression and/or fragrance intensity of a consumer product.

  本发明涉及一种香水组合物，包括至少两种从以下组成的适当香气化合物中选择的香气化合物：一种在光照下释放香水化合物的前香水化合物，一种在空气/氧气暴露下释放香水化合物的前香水化合物，一种在热暴露下释放香水化合物的前香水化合物，一种在湿气暴露下释放香水化合物的前香水化合物以及一种在酶暴露下释放香水化合物的前香水化合物。本发明进一步涉及一种含有创新香水组合物的香水消费产品，以及使用创新香水组合物来改善、增强、赋予和/或修改消费产品的香气印象和/或香气强度。