6-ethyl-5-propyl-1H-pyrimidine-2,4-dione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 6-ethyl-5-propyl-1H-pyrimidine-2,4-dione
• 化学式: C₉H₁₄N₂O₂
• 分子量: 182.22
• InChiKey: AEALQNLGJGIUFU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.56
• 拓扑面积：
  58.2
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• [EN] FUSED CYCLOALKYL-PYRIMIDINE COMPOUNDS AND USES THEREOF<br/>[FR] COMPOSÉS DE CYCLOALKYLE-PYRIMIDINE FUSIONNÉS ET LEURS UTILISATIONS
  申请人：MEDIVATION TECHNOLOGIES INC

  公开号：WO2016003827A2

  公开（公告）日：2016-01-07

  Fused cycloalkyl-pyrimidine compounds that are kinase inhibitors, such as multi-kinase inhibitors, are provided. The compounds may be used in a method of treating cancer. Pharmaceutical compositions containing a fused cycloalkyl-pyrimidine compound and a pharmaceutically acceptable carrier are also provided, as are kits containing a fused cycloalkyl- pyrimidine compound or salt thereof and instructions for use, e.g., in a method of treating cancer.