3-(6-methoxy-1H-benzimidazol-2-yl)propan-1-ol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: 3-(6-methoxy-1H-benzimidazol-2-yl)propan-1-ol
• 化学式: C₁₁H₁₄N₂O₂
• mdl: MFCD03170138
• 分子量: 206.24
• InChiKey: WDXJZYHGTAUNED-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  58.1
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• BENZIMIDAZOLES AND ANALOGUES AND THEIR USE AS PROTEIN KINASES INHIBITORS
  申请人：Aventis Pharmaceuticals Inc.

  公开号：EP1441725A1

  公开（公告）日：2004-08-04
• [EN] BENZIMIDAZOLES AND ANALOGUES AND THEIR USE AS PROTEIN KINASES INHIBITORS<br/>[FR] BENZIMIDAZOLES ET ANALOGUES ET LEUR UTILISATION COMME INHIBITEURS DE PROTEINES KINASES
  申请人：AVENTIS PHARMA INC

  公开号：WO2003035065A1

  公开（公告）日：2003-05-01

  The invention is directed to physiologically active compounds of the general formula (Ix) and compositions containing such compounds, and their prodrugs, and pharmaceutically acceptable salts and solvates of such compounds and their prodrugs, as well as to novel compounds within the scope of formula (Ix), and to processes for their preparation. Such compounds and compositions have valuable pharmaceutical properties, in particular the ability to inhibit kinases.