Bis(1-methyl propenyl) disulfide

• 分子结构分类: 有机化合物 - 有机硫化合物 - 有机二硫化物
• 英文名称: Bis(1-methyl propenyl) disulfide
• 英文别名: (E)-2-[[(E)-but-2-en-2-yl]disulfanyl]but-2-ene
• 化学式: C₈H₁₄S₂
• 分子量: 174.3
• InChiKey: SEUXDSIHTAQGIQ-KQQUZDAGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  50.6
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Method for testing oral malodor
  申请人：Colgate-Palmolive Company

  公开号：US10052045B2

  公开（公告）日：2018-08-21

  The present invention relates to a method for testing oral malodor, in particular oral malodor from onion and garlic. Described herein are methods for testing the efficacy of an oral care composition to reduce oral malodor, the method comprising the steps of: a) cleaning at least a part of the oral cavity with an oral care composition; b) testing a first sample of exhaled breath from the cleaned oral cavity to provide a first test result representing a first amount of at least one oral malodor component detected in the exhaled breath; c) exposing the oral cavity to an oral malodor material including or capable of forming the at least one oral malodor component; and d) testing a second sample of exhaled breath from the oral cavity to provide a second test result representing a second amount of the at least one oral malodor component detected in the exhaled breath.

  本发明涉及一种测试口腔异味，特别是洋葱和大蒜产生的口腔异味的方法。本文描述的是测试口腔护理组合物减少口腔异味功效的方法，该方法包括以下步骤：a) 用口腔护理组合物清洁口腔的至少一部分； b) 测试从清洁过的口腔呼出的口气的第一样本，以提供代表在呼出的口气中检测到的至少一种口腔恶臭成分的第一数量的第一测试结果；c) 将口腔暴露于包括或能够形成至少一种口腔恶臭成分的口腔恶臭材料中；以及 d) 检测来自口腔的第二份呼出气体样本，以提供代表在呼出气体中检测到的至少一种口腔恶臭成分的第二量的第二检测结果。
• Use of asafetida extract as medicine for abstinence of drugs
  申请人：Wang Zemin

  公开号：US20060078570A1

  公开（公告）日：2006-04-13

  The present invention relates to the use of asafetida extract in the preparation of medicine for abstinence of drugs. The present invention further relates to a method for abstinence of drugs, which comprises administering a therapeutically effective amount of asafetida extract to subjects. The asafetida extract according to the present invention may be extracted from factice resin of Ferula sinkiangensis K.M. Shen or Ferula fukanensis K.M. Shen, and consists essentially of α-pinene, α-terpinene, 2-borneol, terpin-4-ol, D-fenchyl alcohol, pinocarveol, β-ocimene A, β-ocimene B, di-sec-butyl disulfide, sec-butyl-trans-1-butenyl disulfide, sec-butyl-cis-propenyl disulfide, sec-butyl-cis-1-butenyl disulfide, sec-butyl-trans-2-butenyl disulfide and thio-sec-butyl-trans-methylethenyl disulfide. The asafetida extract according to the present invention may also be extracted from factice resin of F. assafoetida L from Iran, Afghanistan and the like, and consists essentially of α-pinene, 2-borneol, terpin-4-ol, D-fenchyl alcohol, pinocarveol, dimethyl disulfide, dimethyl trisulfide, methylpropenyl disulfide, 2,2-dimethylthiopropane, 1,2-diethylthiopropane, N,N-dimethylthioformamide and propenylbutyl disulfide. The medicine for abstinence of drugs prepared with asafetida extract according to the present invention is suitable for the use in the abstinence treatment of subjects addicted to opioid, morphine, marijuana, diamorphine and the like.

  本发明涉及asafetida提取物在制备戒毒药物中的用途。本发明进一步涉及一种戒除毒品的方法，该方法包括向受试者施用治疗有效量的asafetida提取物。根据本发明，asafetida 提取物可从以下植物的糠醛树脂中提取 阿魏 沈国明或 呋喃阿魏 K.M. Shen主要成分有α-蒎烯、α-萜品烯、2-龙脑、萜品-4-醇、D-葑醇、蒎烷醇、β-ocimene A、β-ocimene B、二-仲丁基二硫化物、仲丁基-反式-1-丁烯基二硫醚、仲丁基-顺式-丙烯基二硫醚、仲丁基-顺式-1-丁烯基二硫醚、仲丁基-反式-2-丁烯基二硫醚和硫代仲丁基-反式-甲基乙烯基二硫醚。本发明中的阿沙飞陀提取物也可以从阿沙飞陀的树脂中提取。 F. assafoetida 本发明的asafetida提取物也可以从伊朗、阿富汗等地的Factice树脂中提取，主要成分为α-蒎烯、2-龙脑、萜品-4-醇、D-葑醇、蒎烷醇、二甲基二硫化物、二甲基三硫化物、甲基丙烯基二硫化物、2,2-二甲基硫代丙烷、1,2-二乙基硫代丙烷、N,N-二甲基硫代甲酰胺和丙烯基丁基二硫化物。根据本发明，用 Asafetida 提取物制备的戒毒药物适用于对阿片类、吗啡、大麻、二吗啡等成瘾者的戒毒治疗。
• METHOD FOR TESTING ORAL MALODOR
  申请人：COLGATE-PALMOLIVE COMPANY

  公开号：US20150265183A1

  公开（公告）日：2015-09-24

  The present invention relates to a method for testing oral malodor, in particular oral malodor from onion and garlic. Described herein are methods for testing the efficacy of an oral care composition to reduce oral malodor, the method comprising the steps of: a) cleaning at least a part of the oral cavity with an oral care composition; b) testing a first sample of exhaled breath from the cleaned oral cavity to provide a first test result representing a first amount of at least one oral malodor component detected in the exhaled breath; c) exposing the oral cavity to an oral malodor material including or capable of forming the at least one oral malodor component; and d) testing a second sample of exhaled breath from the oral cavity to provide a second test result representing a second amount of the at least one oral malodor component detected in the exhaled breath.
• US4433695A
  申请人：——

  公开号：US4433695A

  公开（公告）日：1984-02-28
• US4476147A
  申请人：——

  公开号：US4476147A

  公开（公告）日：1984-10-09