6-Amino-o-benzoylbenzoesaeure | 68854-23-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 6-Amino-o-benzoylbenzoesaeure
• 英文别名: 6-Amino-2-benzoylbenzoesaeure；2-amino-6-benzoyl-benzoic acid；2-Amino-6-benzoyl-benzoesaeure；3-Amino-benzophenon-carbonsaeure-(2)；2-benzoyl-6-aminobenzoic acid；2-Amino-6-benzoylbenzoic acid
• CAS: 68854-23-9
• 化学式: C₁₄H₁₁NO₃
• 分子量: 241.246
• InChiKey: FSGJAJCMWLFZTF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  80.4
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  6-Amino-o-benzoylbenzoesaeure 、 甲基肼 以 乙醇 、 二氯甲烷 、 甲苯 为溶剂， 以5.40 g (79%)的产率得到2-methyl-4-phenyl-8-amino-1-(2H)-phthalazinone hydrochloride
  参考文献：
  名称：

  Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine

  摘要：

  芳基融合和杂环融合的2,4-二氮杂环化合物的化学式为XXXVI，苯二氮杂环化合物的化学式为XXX，苯二氮杂环化合物的化学式为II，Δ-氨基酰胺的化学式为III，芳基二甲胺的化学式为XXXVII，其中A为芳基或杂环环；R.sup.1为氢、烷基、芳基或杂环基；R.sup.2为氢、烷基、取代烷基或芳基；R.sup.3为烷基、芳基、芳基烷基或杂原子取代的烷基或芳基；R.sup.4为氢或烷基；R.sup.5为氢、烷基、芳基或杂环基；R.sup.6为氢、烷基、烷氧基、卤素或融合苯环；R.sup.9为氢、烷基或取代烷基；R.sup.10为氢、烷基或取代烷基。该发明还涉及制备过程、含有药物组合物的制药组合物以及使用化合物XXXVI、XXX、II、III和XXXVII治疗心律失常的方法。

  公开号：

  US05380721A1
• 作为产物：
  描述：

  2-苯甲酰基-6-硝基苯甲酸 在 氨 、 iron(II) sulfate 作用下， 生成 6-Amino-o-benzoylbenzoesaeure
  参考文献：
  名称：

  Lawrance, Journal of the American Chemical Society, 1920, vol. 42, p. 1876

  摘要：

  DOI：

文献信息

• Method for Making Ionomers Using Amine Compounds Comprising Salt Functional Groups, Ionomers made by the Method and Sports Equipment Comprising Such Ionomers
  申请人：Kim J. Hyun

  公开号：US20070232756A1

  公开（公告）日：2007-10-04

  Ionomeric reaction products are disclosed that are made by combining a monomer, oligomer or polymer having at least one reactive carboxyl group and/or isocyanate group, or functional group or groups equivalent thereto or derived therefrom, with an amine compound having both an amine and an anionic functional group and a formula [RHN—(R 1 ) m —(X − ) n ] o -M a+ p where R is hydrogen, aliphatic, alicyclic, arylaliphatic or aromatic, R 1 is a linking group that links the amine and salt functional groups and is aliphatic, alicyclic, arylaliphatic or aromatic, X is an anionic group, M is a positively charged species, a is 1-4, m is 0 or greater, n is 1-4, o is 1-4 and p is 0-4, more typically 1-4. An amount of the amine compound is used to react with at least a portion of the reactive functional groups. A method for making a golf ball also is disclosed, as are golf balls comprising disclosed ionomers. At least one component of a golf ball, such as a cover layer, is made comprising disclosed ionomers. The golf ball can have any construction suitable for a golf ball, including multi-layered balls, such as a 3- or 4-piece ball.

  本发明公开了离子聚合物反应产物，其通过将至少具有一个反应性羧基和/或异氰酸酯基或等效的功能基团或由其衍生的单体、低聚物或聚合物与一种同时具有胺基和阴离子功能基团的胺化合物结合而制成，其具有以下化学式[RHN—(R1)m—(X−)n]o-Ma+p，其中R为氢、脂肪、脂环、芳基脂肪或芳香族，R1是连接胺基和盐基团的连接基团，为脂肪、脂环、芳基脂肪或芳香族，X为阴离子基团，M为正电荷物种，a为1-4，m为0或更大，n为1-4，o为1-4，p为0-4，更通常为1-4。使用一定量的胺化合物来与至少部分反应性功能基团反应。本发明还公开了一种制造高尔夫球的方法，以及包括所述离子聚合物的高尔夫球。高尔夫球的至少一个组件，如覆盖层，是由所述离子聚合物制成的。高尔夫球可以具有适合高尔夫球的任何结构，包括多层球，如3或4层球。
• COMPOSITIONS COMPRISING AN AMINO TRIAZINE AND IONOMER OR IONOMER PRECURSOR
  申请人：Kim Hyun J.

  公开号：US20090270201A1

  公开（公告）日：2009-10-29

  Disclosed embodiments concern using at least one triazine, typically an amine or polyamine triazine (referred to as amino triazines), in combination with at least one ionomer or ionomer precursor to form compositions useful for making sporting equipment, such as golf ball components. The ionomer or ionomer precursor typically includes plural acid functional groups, such as carboxyl or carboxylate groups, that react or form salts with the amino triazine. Specific examples, without limitation, of suitable amino triazines include guanamine, 6-methyl-1,3,5-triazine-2,4-diamine (acetoguanamine), 6-nonyl-1,3,5-triazine-2,4-diamine (nonylguanamine), 6-phenyl-1,3,5-triazine-2,4-diamine (benzoguanamine) and 2,4,6-triamino-triazine (melamine).

  公开的实施例涉及使用至少一种三嗪，通常是胺或多胺三嗪（称为氨基三嗪），与至少一种离子聚合物或离子聚合物前体结合，形成用于制造运动器材（例如高尔夫球组件）的组合物。离子聚合物或离子聚合物前体通常包括复数酸性官能团，例如羧基或羧酸盐基团，与氨基三嗪反应或形成盐。适当的氨基三嗪的具体示例包括脲胍、6-甲基-1,3,5-三嗪-2,4-二胺（乙酰胍）、6-壬基-1,3,5-三嗪-2,4-二胺（壬基胍）、6-苯基-1,3,5-三嗪-2,4-二胺（苯基胍）和2,4,6-三氨基-三嗪（三聚氰胺）。
• Aryl-fused and hetaryl-fused-2,4-diazocine antiarrhythmic agents
  申请人：STERLING WINTHROP INC.

  公开号：EP0597540A1

  公开（公告）日：1994-05-18

  Aryl-fused- and hetaryl-fused-2,4-diazepines of formula XXXVI, wherein    A is an aryl, cycloalkyl or hetaryl or substituted aryl ring    R¹ is hydrogen, alkyl, aralkyl, aryl, hetaryl or substituted aryl;    R² is hydrogen, alkyl, aralkyl, aryl or substituted alkyl or aryl;    R³ is alkyl, aryl, aralkyl, hetaryl or heteroatom substituted alkyl, aryl, aralkyl or hetaryl;    R⁴ is hydrogen, alkyl or substituted alkyl;    R⁵ is hydrogen, alkyl, aryl, aralkyl, hetaryl or substituted aryl, pharmaceutical compositions containing these and methods of treating cardiac arrhythmia with the compounds of formula XXXVI are disclosed.

  式 XXXVI 的芳基融合-2,4-二氮杂卓和正十八烷基融合-2,4-二氮杂卓、 其中 A 是芳基环、环烷基环、正十八烷基环或取代的芳基环 R¹ 是氢、烷基、芳烷基、芳基、正烷基或取代的芳基； R² 是氢、烷基、芳烷基、芳基或取代的烷基或芳基； R³ 是烷基、芳基、芳烷基、正烷基或杂原子取代的烷基、芳基、芳烷基或正烷基； R⁴ 是氢、烷基或取代的烷基； R⁵ 是氢、烷基、芳基、芳烷基、庚基或取代的芳基、 本发明公开了含有这些化合物的药物组合物以及用式 XXXVI 化合物治疗心律失常的方法。
• Composition for use in golf balls and sports equipment
  申请人：Kim Jin Hyun

  公开号：US20060014898A1

  公开（公告）日：2006-01-19

  The present invention relates to a novel blend composition suitable for use in sports equipment in general and in particular for use in golf ball manufacture. The composition is the reaction product of; A) a polymer of ethylene and/or one or more alpha olefins, and an acid, ester, or anhydride (“Component (A)”); and B) a compound comprising both an amine and a carboxylic acid in the same molecule which may be present in either a neutral or ionic or zwitterionic form (“Component (B)”); and C) a basic metal ion salt, capable of neutralizing the acid groups of Component (A) and/or Component (B). The metal ions including Li + , Na + , K + , Zn + , Co 2+ , Ca 2+ , Ni 2+ , Cu 2+ , Pb 2+ , and Mg 2+ , with Li + , Na + , Zn 2+ , Ca 2+ , and Mg 2+ being preferred, and their salts include those of, for example, formic acid, acetic acid, nitric acid, sulfuric acid, carbonic acid, bicarbonic acid, as well as the metal oxides, hydroxides, and alkoxides (“Component (C)”). The present invention is also embodied in a blend composition including the reaction product of one or more ionomers and Component (B) which is a compound having a general formula (R 2 N) m —R′—(X(O) n OR y ) m , where R is either hydrogen, one or more C 1 -C 20 aliphatic systems, one or more cycloaliphatic systems, one or more aromatic systems, or a combination of these. Also R′ is a bridging group comprising one or more unsubstituted C 1 -C 20 straight chain or branched aliphatic or alicyclic groups, or one or more substituted straight chain or branched aliphatic or alicyclic groups, or one or more aromatic groups, one or more oligomers each containing up to 12 repeating units, and when X is C or S or P, m is 1-3. Also when X=C, n=1 and y=1, and when X=S, n=2 and y=1, and when X=P, n=2 and y=2. The present invention also resides in a golf ball including a core, an outer cover layer; and from 0 to 5 intermediate layers, wherein one or more of said core, outer cover, and/or intermediate layers, if present, includes the aforementioned blend compositions. Finally, the present invention is also embodied in sports equipment items comprising the aforementioned blend compositions.

  本发明涉及一种适用于一般运动器材，尤其适用于高尔夫球制造的新型混合物。该组合物是以下物质的反应产物：A）乙烯和/或一种或多种α-烯烃的聚合物，以及酸、酯或酸酐（"组分（A）"）；B）在同一分子中包含胺和羧酸的化合物，可以中性或离子或齐聚物形式存在（"组分（B）"）；以及 C）碱性金属离子盐，能够中和组分（A）和/或组分（B）的酸性基团。金属离子包括 Li + 、Na + , K + , Zn + , Co 2+ Ca 2+ Ni 2+ , Cu 2+ , Pb 2+ 和 Mg 2+ 与 Li + 、Na + 、Zn 2+ Ca 2+ 和 Mg 2+ 它们的盐包括甲酸、乙酸、硝酸、硫酸、碳酸、碳酸氢盐以及金属氧化物、氢氧化物和烷氧基化合物（"组分 (C)"）。 本发明还体现在一种混合组合物中，该组合物包括一种或多种离聚物与组分（B）的反应产物，组分（B）是一种具有通式（R 2 N) m -R′-(X(O) n 或 y ) m 其中 R 是氢、一个或多个 C 1 -C 20 脂族体系、一个或多个环脂族体系、一个或多个芳香族体系，或它们的组合。此外，R′是一个桥基，由一个或多个未取代的 C 1 -C 20 直链或支链脂肪族或脂环族基团，或一个或多个取代的直链或支链脂肪族或脂环族基团，或一个或多个芳香族基团，一个或多个低聚物，每个低聚物最多包含 12 个重复单元，当 X 为 C 或 S 或 P 时，m 为 1-3。另外，当 X=C 时，n=1，y=1；当 X=S 时，n=2，y=1；当 X=P 时，n=2，y=2。本发明还涉及一种高尔夫球，包括一个球芯、一个外包层；以及 0 至 5 个中间层，其中一个或多个所述球芯、外包层和/或中间层（如果存在）包括上述混合成分。最后，本发明还体现在包含上述混合物的运动器材中。
• Polyalkenamer compositions and golf balls prepared therefrom
  申请人：Kim J. Hyun

  公开号：US20060166762A1

  公开（公告）日：2006-07-27

  A golf ball that includes (a) a core comprising a center; (b) an outer cover layer; and (c) one or more intermediate layers; wherein at least one of the core, the outer cover layer, or the intermediate layer comprises a composition that includes (i) at least one polyalkenamer and at least one polyamide or (ii) at least one polyalkenamer. A method for making a golf ball comprising a core, one or more intermediate layers and an outer cover layer is also disclosed, wherein the method includes forming a blend comprising at least one polyalkenamer rubber and at least one polyamide; and injection molding the blend into a spherical mold to form the intermediate or outer cover layer. Also disclosed is a polymer composition that includes at least one polyalkenamer and at least one thermoplastic copolyamide elastomer.

  一种高尔夫球，包括(a)由中心组成的球芯；(b)外包层；和(c)一个或多个中间层；其中球芯、外包层或中间层中的至少一个包括一种组合物，该组合物包括(i)至少一种聚烯酰胺和至少一种聚酰胺或(ii)至少一种聚烯酰胺。还公开了一种制造高尔夫球的方法，该高尔夫球包括一个球芯、一个或多个中间层和一个外包层，其中该方法包括形成一种混合物，该混合物包括至少一种聚烯烃橡胶和至少一种聚酰胺；以及将该混合物注塑到球形模具中，以形成中间层或外包层。还公开了一种聚合物组合物，其中包括至少一种聚烯烃胺和至少一种热塑性共聚酰胺弹性体。