1-Hydroxyphenyl-methoxypropane | 1071715-58-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-Hydroxyphenyl-methoxypropane
• 英文别名: Phenyl(propoxy)methanol
• CAS: 1071715-58-6
• 化学式: C₁₀H₁₄O₂
• 分子量: 166.22
• InChiKey: WHOYMXCSWMAACN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  苯甲醛 、 正丁醇 在 ZSM-5 Zeolite 作用下， 反应 0.33h， 以53.6%的产率得到1-Hydroxyphenyl-methoxypropane
  参考文献：
  名称：

  Ultrafast and Continuous Synthesis of Unaccommodating Inorganic Nanomaterials in Droplet- and Ionic Liquid-Assisted Microfluidic System

  摘要：

  Despite many efforts on the synthesis of inorganic nanomaterials with uniform structure and narrow size distribution in a fast and continuous way, it is still a critical challenge in the chemistry research community due to the uncontrollable mass and heat transfer and the harsh experimental conditions of high temperature and pressure. Here we report a droplet- and ionic liquid-assisted microfluidic (DIM) synthesis method, which takes full advantage of both ionic liquids and droplet-assisted microreaction systems, for an ultrafast, mild, and continuous synthesis of various inorganic nanomaterials that takes only tens of minutes rather than days that are usually needed to synthesize. In particular, unaccommodating inorganic nanomaterials that are difficult to produce, such as nanoporous ZSM-S, gamma-A100H, and beta-FeOOH nanorods, were synthesized in only "20 minutes" of reaction time even with simple instrument. The DIM method delineated herein would offer a breakthrough synthetic approach for functional but unaccommodating inorganic nanomaterials in a continuous and mild manner.

  DOI：

  10.1021/ja2054429

文献信息

• Metal nitrate-catalyzed one-pot oxidative esterification of benzaldehyde with hydrogen peroxide in alcoholic solutions at room temperature
  作者：Márcio José da Silva、Cesar Macedo de Oliveira

  DOI：10.1039/d0nj05671e

  日期：——

  solutions of the soluble metal nitrate salts. The influence of main variables of the reaction, such as catalyst load, temperature, and reactant stoichiometry, was investigated. The size of the carbon chain and steric hindrance played an essential role in the reaction selectivity. While methyl and ethyl alcohols selectively provided ester as the main product (ca. 70–75%) and acetal as the subproduct, the other

  在苯甲醛与过氧化氢的氧化酯化反应中研究了金属硝酸盐催化剂的活性。评价了几种类型的金属硝酸盐（碱金属，碱土金属和过渡金属）作为催化剂。在评估的盐中，Fe（NO 3）3是形成目标产物（即，苯甲酸烷基酯）。在甲醇中，将苯甲醛选择性氧化为苯甲酸，然后酯化为苯甲酸甲酯。催化剂的效率与其较高的路易斯酸度特性相关，这是通过可溶性金属硝酸盐的甲醇溶液的pH测量确定的。研究了反应主要变量的影响，例如催化剂负载，温度和反应物化学计量。碳链的大小和位阻在反应选择性中起着至关重要的作用。而甲基和乙基醇选择性地设置酯为主要产物（约70-75％）和乙缩醛为副产物，其他醇类生成的酯，半缩醛和苯甲酸含量最少。使用便宜的催化剂，绿色氧化剂，温和的条件和较短的反应时间是这一一锅法的积极方面。高TON（大约900）是Fe（NO 3）3的高催化活性的证据。值得注意的是，该方法不依赖配体和其他添加剂。
• [DE] VERFAHREN ZUR BIOTECHNOLOGISCHEN HERSTELLUNG VON ALKOHOLEN, ALDEHYDEN UND CARBONSÄUREN<br/>[EN] BIOTECHNOLOGICAL PROCESS FOR PRODUCING ALCOHOLS, ALDEHYDES AND CARBOXYLIC ACIDS<br/>[FR] PROCEDE DE PREPARATION BIOTECHNOLOGIQUE D'ALCOOLS, D'ALDEHYDES ET D'ACIDES CARBOXYLIQUES
  申请人：BASF AKTIENGESELLSCHAFT

  公开号：WO1995002061A1

  公开（公告）日：1995-01-19

  (DE) Es wird ein Verfahren zur biotechnologischen Herstellung von Alkoholen, Aldehyden und Carbonsäuren durch Oxidation von Verbindungen der Formel R1-C(CH3)=CR2R3, worin R1, R2 und R3 die in der Beschreibung angegebene Bedeutung besitzen, mit Hilfe von Mikroorganismen beschrieben.(EN) A biotechnological process is disclosed for producing alcohols, aldehydes and carboxylic acids by oxidising compounds having the formula R1-C(CH3)=CR2R3, in which R1, R2 and R3 have the meanings given in the description, by means of micro-organisms.(FR) L'invention concerne un procédé de préparation biotechnologique d'alcools, d'aldéhydes et d'acides carboxyliques par oxydation de composés de la formule R1-C(CH3)=CR2R3, où R1, R2 et R3 ont la notation mentionnée dans la description, au moyen de micro-organismes.

  该文中描述了一种生物技术制备醇、醛和碳酸酸的方法，具体涉及氧化特定化学式的化合物（R1-C(CH3)=CR2R3），其中R1、R2和R3有特定的含义，使用微生物进行过程。以下是所有版本的翻译： （DE）一种生物技术生产醇、醛和碳酸酸的方法，通过氧化形如R1-C( )=CR2R3的化合物，其中R1、R2和R3在描述中给出其含义，使用微生物描述。 (EN) A biotechnological process is disclosed for producing alcohols, aldehydes and carboxylic acids by oxidising compounds having the formula R1-C( )=CR2R3, in which R1, R2 and R3 have the meanings given in the descriPTion, by means of micro-organisms. (FR) L'invention concerne un procédé de préparation biotechnologique d'alcools, d'aldéhydes et d'acides carboxyliques par oxydation de composés de la formule R1-C( )=CR2R3, où R1, R2 et R3 ont la notation mentionnée dans la descriPTion, au moyen de micro-organismes. (ES) Se describe un proceso biotécnico para la']) ((PT) "Processo biotécnico para aInitialization de alcohol,醛和碳酸酸，通过氧化具有形式R1-C( )=CR2R3的化合物，其中R1、R2和R3在描述中给出其含义，使用微生物。") (CH) 一种生物技术生产醇、醛和碳酸酸的方法，通过氧化具有形式R1-C( )=CR2R3的化合物，其中R1、R2和R3有特定含义，使用微生物描述。
• VERFAHREN ZUR BIOTECHNOLOGISCHEN HERSTELLUNG VON ALKOHOLEN, ALDEHYDEN UND CARBONSÄUREN
  申请人：BASF AKTIENGESELLSCHAFT

  公开号：EP0707656A1

  公开（公告）日：1996-04-24
• POSITIVE PHOTOACTIVE COMPOUNDS BASED ON 2,6-DINITROBENZYL GROUPS
  申请人：PPG Industries Ohio, Inc.

  公开号：EP0770053B1

  公开（公告）日：1999-08-18
• METAL OXIDE-BASED FINE PARTICLE AND METHOD FOR MANUFACTURING THE SAME, AND RESIN COMPOSITION
  申请人：Iji Masatoshi

  公开号：US20110061567A1

  公开（公告）日：2011-03-17

  A metal oxide-based fine particle includes a metal oxide-based core region; an intermediate region formed on the outer periphery of the core region, the intermediate region having an alkoxyorganosiloxane condensate structure; and a surface region including an organic molecular chain or an organic silicon molecular chain or a reactive functional group.