Methyl-phenyl-phosphinigsaere-dimethylamid | 90565-13-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Methyl-phenyl-phosphinigsaere-dimethylamid
• 英文别名: Methyl-dimethylamino-phenyl-phosphin；N-methyl-N-[methyl(phenyl)phosphanyl]methanamine
• CAS: 90565-13-2
• 化学式: C₉H₁₄NP
• 分子量: 167.191
• InChiKey: UYICABXFZSRGMX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  Methyl-phenyl-phosphinigsaere-dimethylamid 、 溴甲苯 生成 N-(benzyl-bromo-methyl-phenyl-lambda5-phosphanyl)-N-methylmethanamine
  参考文献：
  名称：

  HORNER L.; JORDAN M., PHOSPH. AND SULFUR, 1980, 8, NO 2, 225-234

  摘要：

  DOI：
• 作为产物：
  描述：

  苯基二氯化磷 以 乙醚 为溶剂， 生成 Methyl-phenyl-phosphinigsaere-dimethylamid
  参考文献：
  名称：

  p-Phenylenediphosphine and Related Compounds^1,2

  摘要：

  DOI：

  10.1021/jo01053a073

文献信息

• Horner, Leopold; Jordan, Manfred, Phosphorus and Sulfur and the Related Elements, 1980, vol. 8, p. 225 - 234
  作者：Horner, Leopold、Jordan, Manfred

  DOI：——

  日期：——
• Method for producing orthometalated and orthosubstituted aromatic compounds
  申请人：Pfaltz Andreas

  公开号：US20070149796A1

  公开（公告）日：2007-06-28

  The invention relates to compounds having a structural element of formula (I) in an aromatic hydrocarbon ring, wherein: M represents —Li, —MgX 3 , (C 1 -C 18 -Alkyl) 3 Sn—, —ZnX 3 or —B(O—C 1 C 4 -Alkyl) 2 ; X 1 and X 2 , independent of one another, represent O or N, and C-bound hydrocarbon radicals or heterohydrocarbon radicals are bound to the free bonds of the O and N atoms; group —C═C—, together with C atoms, forms a hydrocarbon aromatic compound and represents X 3 Cl, Br or I. The inventive compounds are easily obtained by directly substituting the hydrogen in the ortho position to the P atom with metalation reagents. The metal atoms can then be substituted by a reactive electrophilic compound. The group —P(X 1 —)(X 2 —) - - - (BH 3 ) 0,1 can then be converted into a secondary phosphine group. The inventive method enables the production of monophosphines and diphosphines even on a large scale, which are valuable ligands for metal complexes serving as catalysts for, e.g. enantioselective hydrogenations.
• p-Phenylenediphosphine and Related Compounds^1,2
  作者：Earl M. Evleth、LeVern D. Freeman、Ross I. Wagner

  DOI：10.1021/jo01053a073

  日期：1962.6
• HORNER L.; JORDAN M., PHOSPH. AND SULFUR, 1980, 8, NO 2, 225-234
  作者：HORNER L.、 JORDAN M.

  DOI：——

  日期：——