N-[1-[(6aR,8R,9aS)-9-methylidene-2,2,4,4-tetra(propan-2-yl)-6a,9a-dihydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-2-oxopyrimidin-4-yl]acetamide | 170112-37-5

分子结构分类

有机化合物 - 有机氮化合物

中文名称

——

中文别名

——

英文名称

N-[1-[(6aR,8R,9aS)-9-methylidene-2,2,4,4-tetra(propan-2-yl)-6a,9a-dihydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-2-oxopyrimidin-4-yl]acetamide

英文别名

——

N-[1-[(6aR,8R,9aS)-9-methylidene-2,2,4,4-tetra(propan-2-yl)-6a,9a-dihydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-2-oxopyrimidin-4-yl]acetamide化学式

CAS

170112-37-5

化学式

C₂₄H₄₁N₃O₆Si₂

mdl

——

分子量

523.777

InChiKey

XMMUCGSJADPOBO-AKIFATBCSA-N

BEILSTEIN

——

EINECS

——

计算性质

辛醇/水分配系数(LogP)：

4.61
重原子数：

35
可旋转键数：

6
环数：

3.0
sp3杂化的碳原子比例：

0.71
拓扑面积：

98.7
氢给体数：

1
氢受体数：

6

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
N-乙酰基-3',5'-O-[1,1,3,3-四(异丙基)-1,3-二硅氧烷二基]胞苷	N4-acetyl-3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)cytidine	85335-73-5	C₂₃H₄₁N₃O₇Si₂	527.765
——	N⁴-acetyl-1-<3,5-O-(tetraisopropyldisiloxane-1,3-diyl)-β-D-erythro-pentofuran-2-ulosyl>cytosine	140859-16-1	C₂₃H₃₉N₃O₇Si₂	525.75
(+)-3’,5’-O-(1,1,3,3-四异丙基-1,3-二硅氧烷)胞苷	3',5'-O-[(1,1,3,3-tetraisopropyl)-1,3-disiloxanediyl]cytidine	69304-42-3	C₂₁H₃₉N₃O₆Si₂	485.728
胞苷	CYTIDINE	65-46-3	C₉H₁₃N₃O₅	243.219
尿嘧啶核苷	uridine	58-96-8	C₉H₁₂N₂O₆	244.204

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	N-[1-[(6aR,8R,9R,9aS)-9-cyano-9-methyl-2,2,4,4-tetra(propan-2-yl)-6,6a,8,9a-tetrahydrofuro[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-2-oxopyrimidin-4-yl]acetamide	1403250-61-2	C₂₅H₄₂N₄O₆Si₂	550.803
——	N-[1-[(2R,3R,4S,5R)-3-cyano-4-[[hydroxy-di(propan-2-yl)silyl]oxy-di(propan-2-yl)silyl]oxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide	1491025-66-1	C₂₅H₄₄N₄O₇Si₂	568.818
——	N-[1-[(6aR,8R,9R,9aR)-9-methyl-9-methylsulfanyl-2,2,4,4-tetra(propan-2-yl)-6,6a,8,9a-tetrahydrofuro[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-2-oxopyrimidin-4-yl]acetamide	1403249-55-7	C₂₅H₄₅N₃O₆SSi₂	571.886
——	N-[1-[(6aR,8R,9R,9aS)-9-azido-9-methyl-2,2,4,4-tetra(propan-2-yl)-6,6a,8,9a-tetrahydrofuro[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-2-oxopyrimidin-4-yl]acetamide	1403249-53-5	C₂₄H₄₂N₆O₆Si₂	566.805
——	1-[(6aR,8R,9R,9aR)-9-chloro-9-methyl-2,2,4,4-tetra(propan-2-yl)-6,6a,8,9a-tetrahydrofuro[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-4-aminopyrimidin-2-one	1403249-59-1	C₂₂H₄₀ClN₃O₅Si₂	518.201
——	(2R,3R,4S,5R)-2-(4-amino-2-oxopyrimidin-1-yl)-4-[[hydroxy-di(propan-2-yl)silyl]oxy-di(propan-2-yl)silyl]oxy-5-(hydroxymethyl)-3-methyloxolane-3-carbonitrile	1491025-69-4	C₂₃H₄₂N₄O₆Si₂	526.781
——	1-[(6aR,8R,9R,9aS)-9-amino-9-methyl-2,2,4,4-tetra(propan-2-yl)-6,6a,8,9a-tetrahydrofuro[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-4-aminopyrimidin-2-one	1403249-67-1	C₂₂H₄₂N₄O₅Si₂	498.77
——	1-[(6aR,8R,9R,9aS)-9-azido-9-methyl-2,2,4,4-tetra(propan-2-yl)-6,6a,8,9a-tetrahydrofuro[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-4-aminopyrimidin-2-one	1403249-66-0	C₂₂H₄₀N₆O₅Si₂	524.768
——	N-[1-[(6aR,8R,9R,9aR)-9-methyl-9-methylsulfonyl-2,2,4,4-tetra(propan-2-yl)-6,6a,8,9a-tetrahydrofuro[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-2-oxopyrimidin-4-yl]acetamide	1403249-62-6	C₂₅H₄₅N₃O₈SSi₂	603.885
——	N-[1-[(6aR,8R,9R,9aS)-9-methyl-2,2,4,4-tetra(propan-2-yl)-9-(triazol-1-yl)-6,6a,8,9a-tetrahydrofuro[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-2-oxopyrimidin-4-yl]acetamide	1403249-64-8	C₂₆H₄₄N₆O₆Si₂	592.843
——	N-[(6aR,8R,9R,9aS)-8-(4-amino-2-oxopyrimidin-1-yl)-9-methyl-2,2,4,4-tetra(propan-2-yl)-6,6a,8,9a-tetrahydrofuro[3,2-f][1,3,5,2,4]trioxadisilocin-9-yl]acetamide	1403249-68-2	C₂₄H₄₄N₄O₆Si₂	540.808
——	2-methylpropyl (2S)-2-[[[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4-cyano-3-[[hydroxy-di(propan-2-yl)silyl]oxy-di(propan-2-yl)silyl]oxy-4-methyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate	1491026-66-4	C₃₆H₆₀N₅O₁₀PSi₂	810.045
——	N-[1-[(2R,3R,4S,5R)-3-cyano-4-hydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide	1491021-51-2	C₁₃H₁₆N₄O₅	308.294
——	N-[1-[(2R,3R,4S,5R)-3-azido-4-hydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-2-oxopyrimidin-4-yl]acetamide	1403567-97-4	C₁₂H₁₆N₆O₅	324.296
——	propan-2-yl (2S)-2-[[[(2R,3S,4R,5R)-4-azido-3-hydroxy-4-methyl-5-[4-(2-methylpropanoylamino)-2-oxopyrimidin-1-yl]oxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate	1605283-90-6	C₂₆H₃₆N₇O₉P	621.587
——	propan-2-yl (2S)-2-[[[(2R,3S,4R,5R)-4-cyano-3-hydroxy-4-methyl-5-[2-oxo-4-(2-propylpentanoylamino)pyrimidin-1-yl]oxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate	1605283-80-4	C₃₁H₄₄N₅O₉P	661.692
——	[(2R,3S,4R,5R)-4-azido-4-methyl-5-[4-(2-methylpropanoylamino)-2-oxopyrimidin-1-yl]-2-[[[[(2S)-1-oxo-1-propan-2-yloxypropan-2-yl]amino]-phenoxyphosphoryl]oxymethyl]oxolan-3-yl] 2-methylpropanoate	1605283-89-3	C₃₀H₄₂N₇O₁₀P	691.678
——	[(2R,3S,4R,5R)-4-cyano-4-methyl-5-[4-(2-methylpropanoylamino)-2-oxopyrimidin-1-yl]-2-[[[[(2S)-1-oxo-1-propan-2-yloxypropan-2-yl]amino]-phenoxyphosphoryl]oxymethyl]oxolan-3-yl] 2-methylpropanoate	1605283-84-8	C₃₁H₄₂N₅O₁₀P	675.676
——	methyl (2S)-2-[[[(2R,3R,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxy-4-methyl-4-methylsulfanyloxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate	1403249-81-9	C₂₁H₂₉N₄O₈PS	528.523
——	[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-4-azido-4-methyl-2-[[[[(2S)-1-oxo-1-propan-2-yloxypropan-2-yl]amino]-phenoxyphosphoryl]oxymethyl]oxolan-3-yl] 2-methylpropanoate	1605283-86-0	C₂₆H₃₆N₇O₉P	621.587