di(tert-butyl)-2,4,6-trimethylphenylphosphine | 578763-02-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: di(tert-butyl)-2,4,6-trimethylphenylphosphine
• 英文别名: Di-tert-butyl(2,4,6-trimethylphenyl)phosphane；ditert-butyl-(2,4,6-trimethylphenyl)phosphane
• CAS: 578763-02-7
• 化学式: C₁₇H₂₉P
• 分子量: 264.391
• InChiKey: ULAQEBGWAPXHGX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  18
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  二叔丁基氯化膦 、 magnesium,1,3,5-trimethylbenzene-6-ide,bromide 在 copper(l) chloride 作用下， 以 四氢呋喃 为溶剂， 反应 5.0h， 以88%的产率得到di(tert-butyl)-2,4,6-trimethylphenylphosphine
  参考文献：
  名称：

  PROCESS FOR PRODUCING TERTIARY PHOSPHINE HAVING BULKY HYDROCARBON GROUP BONDED

  摘要：

  公开号：

  EP1473297B1

文献信息

• [EN] A PROCESS FOR THE REDUCTION OF A TERTIARY PHOSPHINE OXIDE TO THE CORRESPONDING TERTIARY PHOSPHINE IN THE PRESENCE OF A CATALYST AND USE OF A TERTIARY PHOSPHINE FOR REDUCING A TERTIARY PHOSPHINE OXIDE IN THE PRESENCE OF A CATALYST<br/>[FR] PROCÉDÉ DE RÉDUCTION D'UN OXYDE DE PHOSPHINE TERTIAIRE EN LA PHOSPHINE TERTIAIRE CORRESPONDANTE EN PRÉSENCE D'UN CATALYSEUR, ET UTILISATION D'UNE PHOSPHINE TERTIAIRE POUR RÉDUIRE UN OXYDE DE PHOSPHINE TERTIAIRE EN PRÉSENCE D'UN CATALYSEUR
  申请人：CHROMAFORA AB

  公开号：WO2011123037A1

  公开（公告）日：2011-10-06

  A process for the conversion of a tertiary phosphine oxide to the corresponding tertiary phosphine comprising reacting said tertiary phosphine oxide with a reducing tertiary phosphine, in the presence of a catalyst that catalyzes the conversion.

  一种将三级膦氧转化为对应的三级膦的方法，包括在催化剂的存在下，将所述三级膦氧与还原三级膦反应，以催化转化。
• Process for preparing tertiary phosphines
  申请人：——

  公开号：US20030229240A1

  公开（公告）日：2003-12-11

  The invention relates to a process for synthesizing tertiary phosphines by reacting halophosphines with organomagnesium compounds in the presence of copper compounds and optionally of salts.

  本发明涉及一种合成三级膦化合物的方法，通过在铜化合物和可选盐的存在下，将卤化膦化合物与有机镁化合物反应。
• Process for producing tertiary phosphine having bulky hydrocarbon group bonded
  申请人：Maehara Shinya

  公开号：US20060020148A1

  公开（公告）日：2006-01-26

  A production process by which tertiary phosphine with an attached sterically bulky hydrocarbon group is produced in a high yield and with high purity on an industrial scale through simple and safe operations by allowing a dialkylphosphinous halide to react with a Grignard reagent in the presence of a copper compound in an amount corresponding to 0.1 to 5% by mol based on the dialkylphosphinous halide to produce tertiary phosphine represented by the following formula (3): wherein R 1 and R 2 are each a tertiary hydrocarbon group of 4 to 13 carbon atoms, and R 3 is an alkyl group, an alkenyl group, an aryl group or the like.

  通过简单和安全的操作，在存在铜化合物的情况下，允许二烷基膦酸卤化物与格氏试剂反应，产生带有立体位阻碍的碳氢基团的三级膦酸产物，高产率和高纯度地在工业规模上生产，其中铜化合物的用量相当于以二烷基膦酸卤化物为基础的0.1至5％摩尔。所述三级膦酸的化学式（3）如下：其中R1和R2分别是4至13个碳原子的三级烃基，R3是烷基，烯基，芳基或类似物。
• Process for producing tertiary phosphine
  申请人：Hokko Chemical Industry Co., Ltd.

  公开号：US07250535B2

  公开（公告）日：2007-07-31

  A production process by which tertiary phosphine with an attached sterically bulky hydrocarbon group is produced in a high yield and with high purity on an industrial scale through simple and safe operations by allowing a dialkylphosphinous halide to react with a Grignard reagent in the presence of a copper compound in an amount corresponding to 0.1 to 5% by mol based on the dialkylphosphinous halide to produce tertiary phosphine represented by the following formula (3): wherein R1 and R2 are each a tertiary hydrocarbon group of 4 to 13 carbon atoms, and R3 is an alkyl group, an alkenyl group, an aryl group or the like.

  通过简单安全的操作，使二烷基膦卤化物在铜化合物的存在下与格氏试剂反应，产生带有立体障碍的烷基羟基磷酰胺，从而在工业规模上高产高纯地生产三级磷化物，所述铜化合物的用量相当于基于二烷基膦卤化物0.1至5％的摩尔比，所述三级磷化合物由以下式（3）表示：其中R1和R2均为4至13个碳原子的三级烃基，而R3为烷基，烯基，芳基或类似基团。
• PROCESS FOR THE REDUCTION OF A TERTIARY PHOSPHINE OXIDE TO THE CORRESPONDING TERTIARY PHOSPHINE IN THE PRESENCE OF A CATALYST AND USE OF A TERTIARY PHOSPHINE FOR REDUCING A TERTIARY PHOSPHINE OXIDE IN THE PRESENCE OF A CATALYST
  申请人：Laven Gaston

  公开号：US20130012725A1

  公开（公告）日：2013-01-10

  A process for the conversion of a tertiary phosphine oxide to the corresponding tertiary phosphine includes reacting the tertiary phosphine oxide with a reducing tertiary phosphine, in the presence of a catalyst that catalyzes the conversion.

  将三级膦氧化物转化为相应的三级膦的过程包括在催化剂的存在下，将三级膦氧化物与还原三级膦反应，催化剂催化转化。