4,9-Dimethoxy-5,8-dihydro[1,3]dioxolo[4,5-g]quinoxaline-6,7-dione

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 4,9-Dimethoxy-5,8-dihydro[1,3]dioxolo[4,5-g]quinoxaline-6,7-dione
• 英文别名: 4,9-dimethoxy-5,8-dihydro-[1,3]dioxolo[4,5-g]quinoxaline-6,7-dione
• 化学式: C₁₁H₁₀N₂O₆
• mdl: MFCD30711885
• 分子量: 266.21
• InChiKey: DIRXZVNEYODDPQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  95.1
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  洋芹脑 在 盐酸 、 氢气 、 硝酸 、 臭氧 、 potassium hydroxide 作用下， 以 吡啶 、 甲醇 、 氯仿 、 水 为溶剂， 100.0 ℃ 、3.0 MPa 条件下， 反应 16.67h， 生成 4,9-Dimethoxy-5,8-dihydro[1,3]dioxolo[4,5-g]quinoxaline-6,7-dione
  参考文献：
  名称：

  Dill and parsley seed extracts in scale up synthesis of aminopolyalkoxybenzenes – beneficial synthons for fused nitrogen polyalkoxyheterocycles

  摘要：

  Ecologically friendly transformation of readily accessible plant allylpolyalkoxybenzenes to hardly available aminotetraalkoxybenzenes has been developed. The efficacy of hydrogenation stage is substantially increased by the application of highly porous ceramic block Pd-catalysts featuring a large surface area, low hydraulic resistance, significant thermal and mechanical stabililty, multiple cycling and easy regeneration.

  DOI：

  10.1016/j.mencom.2016.01.026

文献信息

• Dill and parsley seed extracts in scale up synthesis of aminopolyalkoxybenzenes – beneficial synthons for fused nitrogen polyalkoxyheterocycles
  作者：Irina B. Karmanova、Sergei I. Firgang、Leonid D. Konyushkin、Victor N. Khrustalev、Alexander V. Ignatov、Leonid A. Kuznetsov、Yuriy A. Pinchuk、Ivan A. Kozlov、Victor V. Semenov

  DOI：10.1016/j.mencom.2016.01.026

  日期：2016.1

  Ecologically friendly transformation of readily accessible plant allylpolyalkoxybenzenes to hardly available aminotetraalkoxybenzenes has been developed. The efficacy of hydrogenation stage is substantially increased by the application of highly porous ceramic block Pd-catalysts featuring a large surface area, low hydraulic resistance, significant thermal and mechanical stabililty, multiple cycling and easy regeneration.