2-methoxymethyl-3-methyl-furan | 1158209-88-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 杂芳族化合物
• 英文名称: 2-methoxymethyl-3-methyl-furan
• 英文别名: 2-(methoxymethyl)-3-methylfuran
• CAS: 1158209-88-1
• 化学式: C₇H₁₀O₂
• 分子量: 126.155
• InChiKey: OXEMOGOJELVSLC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.43
• 拓扑面积：
  22.4
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  (3-甲基-2-呋喃基)甲醇 、 碘甲烷 以 四氢呋喃 为溶剂， 生成 2-methoxymethyl-3-methyl-furan
  参考文献：
  名称：

  NEW AMINOTHIAZOLES AS FBPASE INHIBITORS FOR DIABETES

  摘要：

  式(I)的化合物以及其药用可接受的盐和酯，其中R1至R3具有权利要求1中给定的含义，并可用于制成药物组合物。

  公开号：

  US20090143448A1

文献信息

• Aminothiazoles as FBPase inhibitors for diabetes
  申请人：Hoffman-La Roche Inc.

  公开号：US07973051B2

  公开（公告）日：2011-07-05

  Compounds of formula (I) as well as pharmaceutically acceptable salts and esters thereof, wherein R1 to R3 have the significance given in claim 1 and which can be used in the form of pharmaceutical compositions.

  化合物(I)的公式，以及其药学上可接受的盐和酯，其中R1到R3具有权利要求1中给出的意义，并且可以用于制成药物组成物的形式。
• BIARYL DERIVATIVE
  申请人：Shionogi Co., Ltd.

  公开号：EP1798224A1

  公开（公告）日：2007-06-20

  The present invention provides a compound represented by the formula (I): wherein X1 is N or CR2, X2 is N or CR4, R1 to R6 are each independently hydrogen, halogen, lower alkyl, lower alkoxy etc., a broken line is a single bond or a double bond etc., Y is COORA, CONHB(CRCRD)PCOORA, CONRERF, CONRB(CRCRD)pCONRERF etc., RA to RF, RH and RJ are each independently hydrogen, lower alkyl etc., RG is lower alkyl, aryl heterocycle etc., p is 1 or 2, ring A is optionally substituted phenyl, optionally substituted indolyl etc., X3 is O, S or NR13, X4 is CR7 or N, X5 is CR8 or N, X6 is CR9 or N, X7 is CR10 or N, R7 to R12 are each independently hydrogen, halogen, lower alkyl etc., R13 and R14 are each independently hydrogen, lower alkyl etc., W is hydrogen, lower alkyl, NR15R16 etc., and R15 to R21 are each independently hydrogen, lower alkyl etc.), or a pharmaceutically acceptable salt or a solvate thereof, and a pharmaceutical composition containing them.

  本发明提供了一种由式 (I) 表示的化合物： 其中X1是N或CR2，X2是N或CR4，R1至R6各自独立地是氢、卤素、低级烷基、低级烷氧基等，断线是单键或双键等，Y是COORA、CONHB(CRCRD)PCOORA、CONRERF、CONRB(CRCRD)PCONRERF等，RA至RF、RH和RJ各自独立地是氢、低级烷基等，RG是低级烷基、芳基杂环等、p 是 1 或 2，环 A 是任选取代的苯基、任选取代的吲哚基等，X3 是 O、S 或 NR13，X4 是 CR7 或 N，X5 是 CR8 或 N，X6 是 CR9 或 N，X7 是 CR10 或 N，R7 至 R12 各自独立地是氢、卤素、低级烷基等，R13 和 R14 各自独立地是氢、低级烷基等，W 是氢、低级烷基、NR15R16 等，R15 至 R21 各自独立地是氢、低级烷基等、） 或其药学上可接受的盐或溶液，以及含有它们的药物组合物。
• AMINOTHIAZOLE DERIVATIVES
  申请人：F. Hoffmann-La Roche AG

  公开号：EP2227468A1

  公开（公告）日：2010-09-15
• ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, MASK BLANKS INCLUDING ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, PATTERN FORMING METHOD AND PHOTOMASK
  申请人：FUJIFILM Corporation

  公开号：US20150086911A1

  公开（公告）日：2015-03-26

  An actinic ray-sensitive or radiation-sensitive resin composition includes; a compound (A) which generates an acid by irradiation with actinic rays or radiation, wherein the acid is linked with a group represented by the following general formula (M) through covalent bonding. In the formula, Y 1 and Y 2 each independently represent a hydrogen atom, an alkyl group, a cycloalkyl group, an alkenyl group, an alkynyl group, an aryl group, or an acyl group. Z represents a hydrogen atom or a substituent. * represents a linking site with a residue of the compound (A)
• US7973051B2
  申请人：——

  公开号：US7973051B2

  公开（公告）日：2011-07-05