N-[2,6-di(propan-2-yl)phenyl]-1-[2-(2,4,6-tritert-butylphenyl)phosphanylphenyl]methanimine | 1107595-12-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-[2,6-di(propan-2-yl)phenyl]-1-[2-(2,4,6-tritert-butylphenyl)phosphanylphenyl]methanimine
• CAS: 1107595-12-9
• 化学式: C₃₇H₅₂NP
• 分子量: 541.8
• InChiKey: BFCVTZDWAWEQAG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  11.6
• 重原子数：
  39
• 可旋转键数：
  9
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.49
• 拓扑面积：
  12.4
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N-[2,6-di(propan-2-yl)phenyl]-1-[2-(2,4,6-tritert-butylphenyl)phosphanylphenyl]methanimine 在 potassium hydride 作用下， 以 四氢呋喃 、 氘代苯 为溶剂， 反应 1.0h， 以100%的产率得到2-[2,6-Di(propan-2-yl)phenyl]-2,1-benzazaphosphole
  参考文献：
  名称：

  Unexpected Cyclization Reaction of an Overcrowded 2-Phosphinophenylmethanimine Derivative Leading to the Formation of the First Stable 2-Phospha-2H-isoindole Derivative

  摘要：

  The reaction of overcrowded 2-phosphinophenylmethanimine derivative I bearing a 2,4,6-tri-t-butylphenyl (Mes*) group on the phosphorus atom and a 2,6-diisopropylphenyl (Dip) group on the nitrogen atom with potassium hydride afforded 2-phospha-2H-isoindole 2 along with Mes*H.

  DOI：

  10.3987/com-08-s(n)36
• 作为产物：
  描述：

  2-(2,4,6-Tritert-butylphenyl)phosphanylbenzaldehyde 、 2,6-二异丙基苯胺 在 三氟化硼乙醚 作用下， 以 甲苯 为溶剂， 反应 13.0h， 以100%的产率得到N-[2,6-di(propan-2-yl)phenyl]-1-[2-(2,4,6-tritert-butylphenyl)phosphanylphenyl]methanimine
  参考文献：
  名称：

  Unexpected Cyclization Reaction of an Overcrowded 2-Phosphinophenylmethanimine Derivative Leading to the Formation of the First Stable 2-Phospha-2H-isoindole Derivative

  摘要：

  The reaction of overcrowded 2-phosphinophenylmethanimine derivative I bearing a 2,4,6-tri-t-butylphenyl (Mes*) group on the phosphorus atom and a 2,6-diisopropylphenyl (Dip) group on the nitrogen atom with potassium hydride afforded 2-phospha-2H-isoindole 2 along with Mes*H.

  DOI：

  10.3987/com-08-s(n)36

文献信息

• Synthesis of rhodium–carbonyl complexes bearing a novel P,N-chelating ligand of Schiff-base type
  作者：Takahiro Sasamori、Teruyuki Matsumoto、Norihiro Tokitoh

  DOI：10.1016/j.poly.2009.06.043

  日期：2010.1

  Schiff-base type N,P-chelating ligands, phosphorus analogues of imino-anilido ligands, were designed and synthesized as a new type of ligands toward transition metals, and the rhodium-carbonyl complexes bearing the novel imino-phosphido and phosphaalkenyl-anilido ligands were synthesized as stable crystalline compounds. Their structures were definitively revealed by X-ray crystallographic analysis, showing the unique electronic features of the ligands. In addition, the effective trans-influence of the phosphorus atom was suggested on the basis of the structural parameters and spectroscopic features of the isolated complexes. (C) 2009 Elsevier Ltd. All rights reserved.