2-Tert-butyl-4-chloro-5-ethoxypyridazin-3-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 2-Tert-butyl-4-chloro-5-ethoxypyridazin-3-one
• 化学式: C₁₀H₁₅ClN₂O₂
• 分子量: 230.69
• InChiKey: QMRGPNHBBFGADA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  15
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  41.9
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-Tert-butyl-4-chloro-5-ethoxypyridazin-3-one 生成 2-tert-butyl-5-ethoxy-4-methoxypyridazin-3-one
  参考文献：
  名称：

  HYMATA, TATSUO;OGURA, TOMOYUKI;XIRATA, KIMINORI;KUDO, SEHJKI

  摘要：

  DOI：

文献信息

• COMPOUND SUITABLE FOR DETECTION OF MITOCHONDRIAL COMPLEX-1
  申请人：HAMAMATSU PHOTONICS K.K.

  公开号：US20150225368A1

  公开（公告）日：2015-08-13

  Provided is a compound represented by formula (1-0): wherein in formula (1-0), R represents —O(CH 2 ) n —, —O(CH 2 ) n OC 2 H 4 —, —CH 2 O(CH 2 ) n — or —CH 2 O(CH 2 ) n OC 2 H 4 —; n represents an integer from 1 to 5; and Q 1 represents F or —OCH 3 .

  提供的化合物的化学式为（1-0）：其中在化学式（1-0）中，R代表—O(CH2)n—，—O( )nOC2H4—，— O( )n—或— O( )nOC2H4—；n代表1到5之间的整数；Q1代表F或—OCH3。
• DIAGNOSTIC AGENT FOR THERAPEUTIC EFFECT ON CANCER
  申请人：HAMAMATSU PHOTONICS K.K.

  公开号：US20160256578A1

  公开（公告）日：2016-09-08

  The present invention provides a diagnostic agent for a therapeutic effect on cancer, containing a compound represented by formula (1-0). (In formula (1-0), R represents —O(CH 2 ) n —, —O(CH 2 ) n OC 2 H 4 —, —CH 2 O(CH 2 ) n —, or —CH 2 O(CH 2 ) n OC 2 H 4 —, n represents an integer of 1 to 5, and Q 1 represents F or —OCH 3 .)

  本发明提供了一种用于治疗癌症的诊断试剂，包含由式(1-0)表示的化合物。(在式(1-0)中，R代表—O(CH2)n—，—O( )nOC2H4—，— O( )n—或— O( )nOC2H4—，n代表1至5的整数，Q1代表F或—OCH3。)
• COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS
  申请人：Lantheus Medical Imaging, Inc.

  公开号：US20200230264A1

  公开（公告）日：2020-07-23

  The present invention provides compounds with imaging moieties for imaging a subject. The present invention also relates to systems, compositions, and methods for the synthesis and use of imaging agents, or precursors thereof. An imaging agent precursor may be converted to an imaging agent using the methods described herein. In some cases, a composition or plurality of imaging agents is enriched in 18 F. In some cases, an imaging agent may be used to image an area of interest in a subject, including, but not limited to, the heart, cardiovascular system, cardiac vessels, brain, and other organs.
• US9598399B2
  申请人：——

  公开号：US9598399B2

  公开（公告）日：2017-03-21
• US9872928B2
  申请人：——

  公开号：US9872928B2

  公开（公告）日：2018-01-23