Tricyclopropylamine | 246147-09-1

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: Tricyclopropylamine
• 英文别名: N,N-dicyclopropylcyclopropanamine
• CAS: 246147-09-1
• 化学式: C₉H₁₅N
• 分子量: 137.225
• InChiKey: QJEWDNDJRVJYBY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  10
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  N-苄基-N-环丙基环丙胺 在 palladium on activated charcoal titanium(IV) isopropylate 、 sodium hydroxide 、 四丁基氯化铵 、 氢气 作用下， 以 四氢呋喃 、 甲醇 、 乙醚 、 氯仿 、 水 为溶剂， 20.0~40.0 ℃ 、101.33 kPa 条件下， 反应 14.0h， 生成 Tricyclopropylamine
  参考文献：
  名称：

  Radical Cations of Trialkylamines:  ESR Spectra and Structures

  摘要：

  Novel syntheses of cyclopropyldiisopropylamine (15), di-tert-butylcyclopropylamine (16), dicyclopropylisopropylamine (17), and tricyclopropylamine (18) are described. Hyperfine data were determined by ESR spectroscopy for the radical cations of these trialkylamines, as well as for those of ethyldiisopropylamine (10), diisopropyl-n-propylamine (11), dicyclohexylethylamine (12), diisopropyl-3-pentylamine (14), and 1-azabicyclo[3.3.3]undecane (manxine; 27). The radical cation of triisopropylamine (13) was reexamined under conditions of improved spectral resolution. Coupling constants of the N-14 nucleus and the beta-protons in the radical cations of 18 trialkylamines provide reliable information about the geometries of these species, which are confirmed by theoretical calculations. With the exception of a few oligocyclic amines, for which flattening is impaired by the rigid molecular framework, all of the radical cations should be planar. Correlation between the observed coupling constants of the beta-protons and the calculated values of the dihedral angle theta, defining the conformation of the alkyl substituent or the azacycloalkane, is verified. Upon oxidation, striking changes occur for those amines that have cyclopropyl substituents, because of the tendency of these groups to assume a perpendicular conformation in the neutral amines and a bisected orientation in the corresponding radical cations.

  DOI：

  10.1021/jo990458n

文献信息

• PROCESS FOR PRODUCTION OF BIS-QUATERNARY AMMONIUM SALT, AND NOVEL INTERMEDIATE
  申请人：Okamoto Kuniaki

  公开号：US20120130107A1

  公开（公告）日：2012-05-24

  Object To provide a method for producing a bis-quaternary ammonium salt efficiently and a novel synthetic intermediate thereof. Solution The present invention relates to a method for producing a bis-quaternary ammonium salt represented by a general formula [3] which comprises reacting a disulfonic acid ester represented by a general formula [1] (in the formula, definitions of two R 1 's and T are as described in claim 1 ) with a tertiary amine represented by a general formula [2] (in the formula, definitions of R 3 to R 5 are as described in claim 1 ), and a disulfonic acid ester represented by a general formula [1′] (in the formula, two R 16 's represent independently a halogen atom or a C1-C3 fluoroalkyl group, and two m's represent independently an integer of 1 to 5).

  提供一种高效生产双季铵盐和其新型合成中间体的方法。本发明涉及一种生产由通用式[3]表示的双季铵盐的方法，包括将由通用式[1]表示的二磺酸酯（在该式中，两个R1和T的定义如权利要求1中所述）与由通用式[2]表示的三级胺（在该式中，R3到R5的定义如权利要求1中所述）以及由通用式[1']表示的二磺酸酯（在该式中，两个R16独立表示卤原子或C1-C3氟烷基，两个m独立表示1至5的整数）反应。
• PRODUCTION METHOD OF CARBONYL COMPOUND
  申请人：KUREHA CORPORATION

  公开号：US20150299080A1

  公开（公告）日：2015-10-22

  The present invention is to provide a method of producing a carbonyl compound at a higher yield. The method of producing a carbonyl compound according to the present invention produces a carbonyl compound represented by general formula (I) by subjecting a compound represented by general formula (II) to dealkoxycarbonylation in the presence of a hydrogen halide salt of tertiary amine. In the formula, R represents an alkyl group having from 1 to 4 carbons.

  本发明提供了一种以更高产率生产酮基化合物的方法。根据本发明的生产酮基化合物的方法通过在三级胺的氢卤化盐存在下，使通式（II）表示的化合物经脱烷氧羰化反应产生通式（I）表示的酮基化合物。在该式中，R代表具有1至4个碳原子的烷基基团。
• PROCESS FOR PRODUCING ESTER COMPOUND
  申请人：Imazeki Shigeaki

  公开号：US20100324314A1

  公开（公告）日：2010-12-23

  PROBLEM To provide an environmentally-friendly method for producing industrially an ester compound. SOLUTION The present invention is a method for producing an ester compound which comprises subjecting a carboxylic acid and an alcohol to dehydration-condensation reaction using an involatile acid catalyst and then removing the residual acid catalyst by bringing a weak basic substance into contact with the residual acid catalyst.

  问题提供一种生产工业酯化合物的环保方法。 解决方案是一种生产酯化合物的方法，包括将羧酸和醇经过脱水缩合反应，使用一种不挥发的酸催化剂，然后通过将弱碱性物质与残留的酸催化剂接触来去除残留的酸催化剂。
• IONIC LIQUID CONTAINING ALLYLSULFONATE ANION
  申请人：Watahiki Tsutomu

  公开号：US20120157680A1

  公开（公告）日：2012-06-21

  PROBLEM: Providing a novel ionic liquid, which is low-cost, environment-friendly, and has low viscosity and melting point. MEANS FOR SOLVING THE PROBLEM: The present invention is the invention of the ionic liquid represented by the general formula [1]: wherein, R 1 to R 3 and n pieces of R 4 each independently represent hydrogen atom or alkyl group having 1 to 4 carbon atoms, R 5 to R 7 each independently represent alkyl group, aralkyl group, or aryl group, R 8 represents alkyl group, aralkyl group, aryl group, or the one represented by the general formula [2]: (wherein T represents alkylene chain having 1 to 8 carbon atoms, n represents 1 or 2, and R 1 to R 7 are the same as the above-described), X represents nitrogen atom or phosphorus atom, n represents 1 or 2. When n is 1, R 3 and R 4 are bound and may form cyclohexene ring together with the adjacent carbon atoms. In addition, when X is nitrogen atom, R 5 to R 7 or R 5 to R 6 may form hetero ring with nitrogen atom binding thereto}.

  问题：提供一种新型离子液体，成本低、环保，并具有低粘度和熔点。 解决问题的方法：本发明是一种由通式[1]表示的离子液体的发明：其中，R1到R3和n个R4分别独立表示氢原子或具有1到4个碳原子的烷基基团，R5到R7分别独立表示烷基基团、芳基烷基基团或芳基基团，R8表示烷基基团、芳基烷基基团、芳基基团或由通式[2]表示的基团：（其中T表示具有1到8个碳原子的烷基链，n表示1或2，R1到R7与上述相同），X表示氮原子或磷原子，n表示1或2。当n为1时，R3和R4结合并且可能与相邻碳原子一起形成环己烯环。此外，当X为氮原子时，R5到R7或R5到R6可能与结合在一起的氮原子形成杂环}。
• PYRAZOLE-BASED CYANINE DYE CONTAINING QUATERNARY AMMONIUM CATION
  申请人：Yamamoto Naoyuki

  公开号：US20120046474A1

  公开（公告）日：2012-02-23

  Problem Provided is a novel cyanine dye derivative having high fluorescence intensity in a short wavelength region, a structure where a pyrazole skeleton and an indole skeleton are bound to a polymethine chain, and also a controllable migration velocity by further introducing a quaternary ammonium cation into a molecule having said structure. Solution The present invention is the invention of a compound represented by the general formula [1] or a salt thereof: [wherein R 1 to R 6 each independently represent an alkyl group having, as a substituent, a group represented by the general formula [101]: (wherein R 101 to R 104 each independently represent a hydrogen atom or an alkyl group of C 1 to C 3 and m represents an integer from 2 to 6, and two or three of R 102 to R 104 together with a nitrogen atom to which they are bound may form a heterocyclic ammonium cation); or a group derived from a carboxylic acid represented by the general formula [2] which may have an amide bond: —COOR 12 [2] (wherein R 12 represents a hydrogen atom, an alkyl group of C 1 to C 10 , an alkali metal atom, an organic ammonium ion, an ammonium ion or anion); or an alkyl group which may have, as a substituent, a group derived from a sulfonic acid represented by the general formula [3] which may have an amide bond: —SO 3 R 13 [3] (wherein R 13 represents a hydrogen atom, an alkali metal atom, an organic ammonium ion, an ammonium ion or anion); R 7 to R 10 each independently represent an alkyl group, an alkynyl group, an aryl group, an alkoxy group, an aryloxy group, an alkylsulfonyl group, an arylsulfonyl group, an amino group, a group derived from a carboxylic acid represented by the general formula [2], a group derived from a sulfonic acid represented by the general formula [3], a halogen atom, a hydrogen atom, a hydroxyl group, a cyano group or a nitro group; R 11 represents a hydrogen atom, an alkyl group, an alkynyl group or an aryl group, and n represents an integer from 0 to 3, and at least one of R 1 to R 6 is an alkyl group having, as a substituent, a group represented by the general formula [101]].

  提供的问题是一种新型青菁染料衍生物，在短波长区域具有高荧光强度，具有吡唑骨架和吲哚骨架结合到聚甲烯链的结构，通过进一步将季铵阳离子引入具有所述结构的分子，还具有可控的迁移速度。 解决方案是一种由通用式[1]表示的化合物或其盐的发明： [其中R1至R6各自独立地表示具有作为取代基的烷基基团的基团的烷基基团，所述基团由通用式[101]表示： （其中R101至R104各自独立地表示氢原子或C1至C3的烷基基团，m表示2至6的整数，且R102至R104中的两个或三个与它们结合的氮原子可能形成杂环铵阳离子）；或者源自可能具有酰胺键的通用式[2]所表示的羧酸的基团： —COOR12 （其中R12表示氢原子、C1至C10的烷基基团、碱金属原子、有机铵离子、铵离子或阴离子）；或者可能具有源自可能具有酰胺键的通用式[3]所表示的磺酸的基团： —SO3R13 （其中R13表示氢原子、碱金属原子、有机铵离子、铵离子或阴离子）；R7至R10各自独立地表示烷基基团、炔基基团、芳基基团、烷氧基团、芳氧基团、烷基磺基团、芳基磺基团、氨基团、源自通用式[2]所表示的羧酸的基团、源自通用式[3]所表示的磺酸的基团、卤素原子、氢原子、羟基、氰基或硝基；R11表示氢原子、烷基基团、炔基基团或芳基基团，n表示0至3的整数，且R1至R6中至少有一个是具有作为取代基的基团的烷基基团，所述基团由通用式[101]表示]。