N-methyl-5-carboxy-m-phenylenediamine | 25026-15-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-methyl-5-carboxy-m-phenylenediamine
• 英文别名: 3-Amino-5-methylamino-benzoesaeure；3-Amino-5-(methylamino)benzoic acid
• CAS: 25026-15-7
• 化学式: C₈H₁₀N₂O₂
• 分子量: 166.18
• InChiKey: SXEIWXHUUMRYAU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  75.4
• 氢给体数：
  3
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  3,5-二氨基苯甲酸 、 碳酸二甲酯 在 zeolite NaY 作用下， 反应 120.0h， 以64%的产率得到N-methyl-5-carboxy-m-phenylenediamine
  参考文献：
  名称：

  Highly selective zeolite-catalysed mono-N-alkylation of arylenediamines by dialkyl carbonates

  摘要：

  Arylenediamines are mono-N-alkylated by dialkyl carbonates in the presence of NaY zeolite catalyst in a regioselective and nontoxic process. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.12.131

文献信息

• Method For The Production Of Monoalkylated Diamines
  申请人：Russ Werner Hubert

  公开号：US20080125603A1

  公开（公告）日：2008-05-29

  Process for preparing alkylated amines The present invention relates to a process for preparing a compound of the formula (I) by reacting a compound of the formula (II) with a compound of the formula (III) (RO) 2 CO (III) or a compound of the formula (IV) in the presence of a zeolite of the NaY faujasite type, where Ar, X, R and n are each as defined in claim 1.

  制备烷基化胺的方法本发明涉及一种制备式(I)化合物的方法，该方法通过在NaY沸石存在下，将式(II)化合物与式(III)(RO)2CO(III)化合物或式(IV)化合物反应，其中Ar、X、R和n如权利要求1所定义。
• Elansolids, Novel Natural Metabolites of Flexibacter and Antibiotically Active Derivatives Thereof
  申请人：Gerth Klaus

  公开号：US20110034528A1

  公开（公告）日：2011-02-10

  The present invention describes Elansolids, a new class of novel anti-bacterial compounds of formula (I).
• [EN] ELANSOLIDS, NOVEL NATURAL METABOLITES OF FLEXIBACTER AND ANTIBIOTICALLY ACTIVE DERIVATIVES THEREOF<br/>[FR] ÉLANSOLIDES, NOUVEAUX MÉTABOLITES NATURELS DE FLEXIBACTER ET DÉRIVÉS ANTIBIOTIQUEMENT ACTIFS DE CES DERNIERS
  申请人：HELMHOLTZ INFEKTIONSFORSCHUNG

  公开号：WO2009103534A2

  公开（公告）日：2009-08-27

  The present invention describes Elansolids, a new class of novel anti-bacterial compounds of formula (I).
• [EN] DYE COMPOSITION USING AT LEAST ONE OXIDATION BASE AND AT LEAST ONE PARTICULAR AMINOBENZENE COUPLER, PROCESSES AND DEVICE<br/>[FR] COMPOSITION COLORANTE UTILISANT AU MOINS UNE BASE D'OXYDATION ET AU MOINS UN COUPLEUR D'AMINOBENZÈNE SPÉCIFIQUE, PROCÉDÉS ET DISPOSITIF
  申请人：OREAL

  公开号：WO2017050994A1

  公开（公告）日：2017-03-30

  The present invention relates to a composition for dyeing keratin fibres, in particular human keratin fibres such as the hair, comprising one or more oxidation bases and one or more particular aminobenzene couplers. The invention also relates to a process for dyeing keratin fibres using said composition in the presence of one or more chemical oxidizing agents, and to a multi-compartment device suitable for using said dye composition.
• Highly selective zeolite-catalysed mono-N-alkylation of arylenediamines by dialkyl carbonates
  作者：Warren J. Ebenezer、Michael G. Hutchings、Ken Jones、David A. Lambert、Ian Watt

  DOI：10.1016/j.tetlet.2006.12.131

  日期：2007.2

  Arylenediamines are mono-N-alkylated by dialkyl carbonates in the presence of NaY zeolite catalyst in a regioselective and nontoxic process. (c) 2007 Elsevier Ltd. All rights reserved.