Sodium (R)-2,3-bis(palmitoyloxy)propyl phosphate | 71065-87-7

• 物质功能分类: 化学试剂 - 有机试剂 - 含磷化合物
• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 甘油磷脂
• 英文名称: Sodium (R)-2,3-bis(palmitoyloxy)propyl phosphate
• 英文别名: disodium;[(2R)-2,3-di(hexadecanoyloxy)propyl] phosphate
• CAS: 71065-87-7
• 化学式: C35H67Na2O8P
• 分子量: 692.9
• InChiKey: NFRFUGBXJTXTMZ-QYKZUBHNSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  3.26
• 重原子数：
  46
• 可旋转键数：
  35
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.94
• 拓扑面积：
  125
• 氢给体数：
  0
• 氢受体数：
  8

文献信息

• Functional associative coatings for nanoparticles
  申请人：Hainfeld James F.

  公开号：US20080089836A1

  公开（公告）日：2008-04-17

  Described herein are nanoparticles that are coated with a bilayer of molecules formed from surface binding molecules and amphiphatic molecules. The bilayer coating self assembles on the nanoparticles from readily available materials/molecules. The modular design of the bilayer coated nanoparticles provides a means for readily and efficiently optimizing the properties of the bilayer coated nanoparticle compositions. Also described herein are uses of such nanoparticles in medicine, laboratory techniques, industrial and commerical applications.

  本文描述了一种纳米颗粒，其表面涂覆有由表面结合分子和两亲分子形成的双层分子层。该双层涂层可以自组装在纳米颗粒上，使用易得的材料/分子。双层涂层纳米颗粒的模块化设计提供了一种方便和高效地优化其性质的方法。此外，本文还描述了这种纳米颗粒在医学、实验室技术、工业和商业应用中的用途。
• Catheter assembly
  申请人：Chappa Ralph A.

  公开号：US10596355B2

  公开（公告）日：2020-03-24

  A catheter assembly includes an expandable and collapsible structure having an outer surface. The expandable and collapsible structure is adapted to expand between a contracted state and a dilated state. A coating is disposed on the outer surface of the expandable and collapsible structure. The coating includes a bioactive agent. A sleeve is disposed over the coating. The sleeve is adapted to expand between a compressed state and an enlarged state and to return to the compressed state. The sleeve defines a plurality of openings in the compressed state. An outer diameter of the coating is less than an outer diameter of the sleeve when the expandable and collapsible structure is in the contracted state and greater than the outer diameter of the sleeve when the expandable and collapsible structure is in the dilated state.

  导管组件包括一个具有外表面的可伸缩结构。可伸缩结构可在收缩状态和扩张状态之间伸缩。可伸缩结构的外表面上有一层涂层。涂层包括生物活性剂。涂层上有一个套筒。套筒可在压缩状态和放大状态之间膨胀并返回压缩状态。套筒在压缩状态下限定了多个开口。当可膨胀和可折叠结构处于收缩状态时，涂层的外径小于套筒的外径，而当可膨胀和可折叠结构处于扩张状态时，涂层的外径大于套筒的外径。
• Anti-thrombotic agents and methods of use thereof
  申请人：Temple University—Of The Commonwealth System of Higher Education

  公开号：US11090309B2

  公开（公告）日：2021-08-17

  The present invention is related to compositions and methods for treating platelet-related diseases.

  本发明涉及治疗血小板相关疾病的组合物和方法。
• CATHETER ASSEMBLY
  申请人：SurModics, Inc.

  公开号：EP2588181A1

  公开（公告）日：2013-05-08
• LIPID COATING FOR MEDICAL DEVICES DELIVERING BIOACTIVE AGENT
  申请人：SurModics, Inc.

  公开号：EP2588157A1

  公开（公告）日：2013-05-08