1,2-bis(methylthio)propane | 67560-48-9

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 1,2-bis(methylthio)propane
• 英文别名: 1,2-Bis(methylsulfanyl)propane
• CAS: 67560-48-9
• 化学式: C₅H₁₂S₂
• 分子量: 136.282
• InChiKey: BAQDEJZTORKSME-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  7
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  50.6
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1,2-丙二硫醇 、 碘甲烷 在 sodium 作用下， 以 甲醇 为溶剂， 反应 3.0h， 以93%的产率得到1,2-bis(methylthio)propane
  参考文献：
  名称：

  Liquid sulfur as a reagent: synthesis of polysulfanes with 20 or more sulfur atoms with characterization by UPLC-(Ag⁺)-coordination ion spray-MS

  摘要：

  Diallyl disulfide reacts within minutes with liquid sulfur at 120 degrees C giving a family of diallyl polysulfanes, All(2)S(n) (n=322), characterized by ultra-performance liquid chromatography-(Ag+)-coordination ion spray-mass spectrometry (UPLC-(Ag+)CIS-MS). Similarly, garlic oil (GO), bis-(2-methyl-2-propenyl), bis-(2-chloro-2-propenyl), bis-(3-methyl-2-butenyl), and bis-(2-cyclohexen-1-yl) disulfides all give families of polysulfanes with up to 22 sequential sulfur atoms. New members of families of silver chelators with up to 10 sulfur atoms were found in GO using UPLC-(Ag+)CIS-MS.[GRAPHICS].

  DOI：

  10.1080/17415993.2012.721368

文献信息

• 432. Dithiols. Part XIX. Further studies on the deacetylation of acetylated dithiols
  作者：Peter S. Fitt、L. N. Owen

  DOI：10.1039/jr9570002240

  日期：——
• Sharp,D.W.A.; Miguel,H.T., Israel Journal of Chemistry, 1978, vol. 17, p. 144 - 147
  作者：Sharp,D.W.A.、Miguel,H.T.

  DOI：——

  日期：——
• Boron trifluoride catalyzed addition of disulfides to alkenes
  作者：Marjorie C. Caserio、Cindy L. Fisher、Jhong K. Kim

  DOI：10.1021/jo00222a041

  日期：1985.11
• Liquid sulfur as a reagent: synthesis of polysulfanes with 20 or more sulfur atoms with characterization by UPLC-(Ag⁺)-coordination ion spray-MS
  作者：Kai Wang、Murree Groom、Robert Sheridan、Shaozhong Zhang、Eric Block

  DOI：10.1080/17415993.2012.721368

  日期：2013.4.1

  Diallyl disulfide reacts within minutes with liquid sulfur at 120 degrees C giving a family of diallyl polysulfanes, All(2)S(n) (n=322), characterized by ultra-performance liquid chromatography-(Ag+)-coordination ion spray-mass spectrometry (UPLC-(Ag+)CIS-MS). Similarly, garlic oil (GO), bis-(2-methyl-2-propenyl), bis-(2-chloro-2-propenyl), bis-(3-methyl-2-butenyl), and bis-(2-cyclohexen-1-yl) disulfides all give families of polysulfanes with up to 22 sequential sulfur atoms. New members of families of silver chelators with up to 10 sulfur atoms were found in GO using UPLC-(Ag+)CIS-MS.[GRAPHICS].