2-chloro-5-[4-(trifluoromethyl)-1H-imidazol-2-yl]pyridine | 88625-15-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2-chloro-5-[4-(trifluoromethyl)-1H-imidazol-2-yl]pyridine
• 英文别名: 2-Chloro-5-[5-(trifluoromethyl)-1H-imidazol-2-yl]pyridine；2-chloro-5-[5-(trifluoromethyl)-1H-imidazol-2-yl]pyridine
• CAS: 88625-15-4
• 化学式: C₉H₅ClF₃N₃
• 分子量: 247.607
• InChiKey: IRZKCMPBAYOSPZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  16
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.11
• 拓扑面积：
  41.6
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2-chloro-5-[4-(trifluoromethyl)-1H-imidazol-2-yl]pyridine 在 ammonium hydroxide 作用下， 以 甲醇 为溶剂， 以96 %的产率得到2-(6-chloro-3-pyridyl)-1H-imidazole-4-carbonitrile
  参考文献：
  名称：

  [EN] HERBICIDAL IMIDAZOLE COMPOUNDS
  [FR] COMPOSÉS IMIDAZOLE HERBICIDES

  摘要：

  The present invention relates to compounds of Formula (I) or an agronomically acceptable salt of said compounds wherein Q, R1and R2are as defined herein. The invention further relates to herbicidal compositions which comprise a compound of Formula (I) and to the use of compounds of Formula (I) for controlling weeds, in particular in crops of useful plants.

  公开号：

  WO2023066783A1
• 作为产物：
  描述：

  2-羟基吡啶-5-醛 在 sodium acetate 、 三氯氧磷 作用下， 以 水 为溶剂， 反应 21.0h， 生成 2-chloro-5-[4-(trifluoromethyl)-1H-imidazol-2-yl]pyridine
  参考文献：
  名称：

  WO2020139988A5

  摘要：

  公开号：

  WO2020139988A5

文献信息

• COMPOSITIONS FOR INHIBITING UBIQUITIN SPECIFIC PROTEASE 1
  申请人：Forma Therapeutics, Inc.

  公开号：EP3902802A1

  公开（公告）日：2021-11-03
• [EN] COMPOSITIONS FOR INHIBITING UBIQUITIN SPECIFIC PROTEASE 1<br/>[FR] COMPOSITIONS POUR INHIBER LA PROTÉASE 1 SPÉCIFIQUE DE L'UBIQUITINE
  申请人：FORMA THERAPEUTICS INC

  公开号：WO2020139988A1

  公开（公告）日：2020-07-02

  This disclosure relates to modulating ubiquitin specific protease 1 (USP1) and provides novel chemical compounds useful as inhibitors of USP1, as well as various uses of these compounds. USP1 inhibiting compounds are useful in the treatment of diseases and disorders associated with USP1, such as cancer.
• HERBICIDAL IMIDAZOLE COMPOUNDS
  申请人：[en]SYNGENTA CROP PROTECTION AG

  公开号：WO2024149675A1

  公开（公告）日：2024-07-18

  The present invention relates to compounds of Formula (I) or an agronomically acceptable salt of said compounds wherein Q, R1, R2, R3and m are as defined herein. The invention further relates to herbicidal compositions which comprise a compound of Formula (I) and to the use of compounds of Formula (I) for controlling weeds, in particular in crops of useful plants.
• WO2020139988A5
  申请人：——

  公开号：WO2020139988A5

  公开（公告）日：2022-12-22
• [EN] HERBICIDAL IMIDAZOLE COMPOUNDS<br/>[FR] COMPOSÉS IMIDAZOLE HERBICIDES
  申请人：[en]SYNGENTA CROP PROTECTION AG

  公开号：WO2023066783A1

  公开（公告）日：2023-04-27

  The present invention relates to compounds of Formula (I) or an agronomically acceptable salt of said compounds wherein Q, R1and R2are as defined herein. The invention further relates to herbicidal compositions which comprise a compound of Formula (I) and to the use of compounds of Formula (I) for controlling weeds, in particular in crops of useful plants.