toluene; hydrobromide | 61048-87-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: toluene; hydrobromide
• 英文别名: Toluol; Hydrobromid；Hbr-toluene；toluene;hydrobromide
• CAS: 61048-87-1
• 化学式: BrH*2C₇H₈
• 分子量: 265.193
• InChiKey: BYQADQLDVPAGSR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.57
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  0
• 氢给体数：
  1
• 氢受体数：
  0

文献信息

• PROCESS FOR PREPARING BORONIC ACIDS AND ESTERS IN THE PRESENCE OF MAGNESIUM METAL
  申请人：Dunach Isabel

  公开号：US20110282090A1

  公开（公告）日：2011-11-17

  The present invention relates to the process for preparing a boronic acid or ester chemically, in which an aromatic compound is reacted with a boronating agent, in the presence of magnesium metal (Mg 0 ). The invention also relates to the boronic acids or esters that can be obtained by means of this process and to the use thereof for example as a synthesis intermediate, in the Suzuki reaction, in the pharmaceutical or alternatively electronics field.

  本发明涉及一种制备硼酸或酯的化学过程，其中芳香化合物在镁金属（Mg0）存在下与硼化剂发生反应。该发明还涉及通过该过程可以获得的硼酸或酯，以及其作为合成中间体、在Suzuki反应中、在制药或电子领域中的用途。
• [EN] 1-(4-(2-((1-(3,4-DIFLUOROPHENYL)-1H-PYRAZOL-3-YL)METHOXY)ETHYL) PIPERAZIN-1-YL)ETHANONE SALTS<br/>[FR] SELS DE 1-(4-(2-((1-(3,4-DIFLUOROPHÉNYL)-1H-PYRAZOL-3-YL)MÉTHOXY)ÉTHYL) PIPÉRAZIN-1-YL)ÉTHANONE
  申请人：ESTEVE LABOR DR

  公开号：WO2017037166A1

  公开（公告）日：2017-03-09

  The present invention relates to 1 -(4-(2-((1 -(3,4-difluorophenyl)-1 H-pyrazol-3-yl)methoxy)ethyl)piperazin-1 -yl)ethanone salts, specifically to the hydrochloride and to the maleate, to pharmaceutical compositions comprising them, and to their use in therapy and/or prophylaxis of sigma receptor associated diseases.

  本发明涉及1-(4-(2-((1-(3,4-二氟苯基)-1H-吡唑-3-基)甲氧基)乙基)哌嗪-1-基)乙酰胺盐，特别是盐酸盐和马来酸盐，涉及含有它们的药物组合物，以及它们在治疗和/或预防与σ受体相关疾病中的用途。
• PROCESS FOR PRODUCTION OF QUINUCLIDINE COMPOUNDS
  申请人：Kitagawa Yutaka

  公开号：US20130060036A1

  公开（公告）日：2013-03-07

  Provided is a production method for a cis-QMF, which has a low environmental burden and is industrially advantageous. Specifically provided is a production method for a cis-type 2-alkylspiro(1,3-oxathiolane-5,3′)quinuclidine hydrochloride, including: reacting a cis-trans isomer mixture of 2-alkylspiro(1,3-oxathiolane-5,3′)quinuclidine with p-nitrobenzoic acid; resolving the resultant product to produce a cis-type 2-alkylspiro(1,3-oxathiolane-5,3′)quinuclidine p-nitrobenzoate; and converting the p-nitrobenzoate into a hydrochloride.

  提供了一种生产cis-QMF的方法，该方法具有低环境负担且在工业上具有优势。具体提供了一种用于生产顺式2-烷基螺(1,3-噁硫杂环戊烷-5,3′)喹啉盐酸盐的方法，包括：将2-烷基螺(1,3-噁硫杂环戊烷-5,3′)喹啉的顺反异构体混合物与对硝基苯甲酸反应；将所得产物分离以产生顺式2-烷基螺(1,3-噁硫杂环戊烷-5,3′)喹啉对硝基苯甲酸酯；并将对硝基苯甲酸酯转化为盐酸盐。
• Selective catalytic photochlorination of 1,1-dichloroethane
  申请人：THE DOW CHEMICAL COMPANY

  公开号：EP0096404A1

  公开（公告）日：1983-12-21

  The invention is a selective process for preparing 1,1,1-trichloroethane comprising irradiating a vaporous mixture comprising 1,1-dichloroethane, chlorine and an effective amount of a photocatalyst wherein the photocatalyst is bromine, a compound which liberates bromine in the presence of chlorine, carbon monoxide, nitric oxide or oxygen, with radiation capable of inducing the selective formation of 1,1,1-trichloroethane. Radiation in the wavelength of between about 250 and 550 nanometers is capable of inducing the selective formation of 1,1,1-trichloroethane.

  本发明是一种制备 1,1,1-三氯乙烷的选择性工艺，包括用能诱导选择性形成 1,1,1-三氯乙烷的辐射照射由 1,1-二氯乙烷、氯和有效量的光催化剂组成的气态混合物，其中光催化剂是溴，一种在氯、一氧化碳、一氧化氮或氧存在下能释放溴的化合物。波长在 250 至 550 纳米之间的辐射能够诱导 1,1,1- 三氯乙烷的选择性形成。
• Method for racemization of optically active chrysanthemic acid or its derivatives
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0299760A1

  公开（公告）日：1989-01-18

  Optically active chrysanthemic acid or its derivatives of the formula (wherein X represents a hydroxyl group, a halogen atom, a C₁₋₂₀ alkoxy group or a 2,2-dimethyl-3-isobutenyl-­cyclopropane carboxyl group and * mark shows asymmetric carbon atom) is racemized by allowing it to react with a bromine compound or a SH compound, in the presence of light.

  光学活性菊酸或其衍生物，其式为 (其中 X 代表羟基、卤素原子、C₁₋₂₀烷氧基或 2,2-二甲基-3-异丁烯基环丙烷羧基，* 标记表示不对称碳原子）在光照下与溴化合物或 SH 化合物反应，使其发生外消旋化。