3-acetoxy-benzoic acid p-toluidide | 174840-27-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-acetoxy-benzoic acid p-toluidide
• 英文别名: 3-Acetoxy-benzoesaeure-p-toluidid；[3-[(4-Methylphenyl)carbamoyl]phenyl] acetate
• CAS: 174840-27-8
• 化学式: C₁₆H₁₅NO₃
• 分子量: 269.3
• InChiKey: MWRLITJZPGPKSP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  55.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-acetoxy-benzoic acid p-toluidide 在 diphosphorus pentasulfide 作用下， 以 吡啶 为溶剂， 反应 1.0h， 以90%的产率得到Acetic acid 3-p-tolylthiocarbamoyl-phenyl ester
  参考文献：
  名称：

  The Synthesis of SomeN-[4-Substituted Phenyl]-3-acetoxybenzthioamides and TheirN¹,N³-Disubstituted Amidrazones

  摘要：

  The synthesis of N-[4-substituted phenyl]-3-acetoxythiobenzamides 5 from corresponding carboxamides 4 is described. The reaction of 5 with hydrazine hydrate gave N-1, N-3-disubstituted amidrazones. They were characterized by their N-1-benzylidene derivatives 7. The structures of these compounds were confirmed by IR-spectroscopy.

  DOI：

  10.1080/00397919608003615
• 作为产物：
  描述：

  间乙酰苯甲酸 在 吡啶 、 氯化亚砜 作用下， 反应 4.0h， 生成 3-acetoxy-benzoic acid p-toluidide
  参考文献：
  名称：

  The Synthesis of SomeN-[4-Substituted Phenyl]-3-acetoxybenzthioamides and TheirN¹,N³-Disubstituted Amidrazones

  摘要：

  The synthesis of N-[4-substituted phenyl]-3-acetoxythiobenzamides 5 from corresponding carboxamides 4 is described. The reaction of 5 with hydrazine hydrate gave N-1, N-3-disubstituted amidrazones. They were characterized by their N-1-benzylidene derivatives 7. The structures of these compounds were confirmed by IR-spectroscopy.

  DOI：

  10.1080/00397919608003615

文献信息

• The Synthesis of Some<i>N</i>-[4-Substituted Phenyl]-3-acetoxybenzthioamides and Their<i>N</i>¹,<i>N</i>³-Disubstituted Amidrazones
  作者：Liljana Jovevska、Froska Anastasova、Vasilka Aleksić

  DOI：10.1080/00397919608003615

  日期：1996.1

  The synthesis of N-[4-substituted phenyl]-3-acetoxythiobenzamides 5 from corresponding carboxamides 4 is described. The reaction of 5 with hydrazine hydrate gave N-1, N-3-disubstituted amidrazones. They were characterized by their N-1-benzylidene derivatives 7. The structures of these compounds were confirmed by IR-spectroscopy.