tri-N-ethyl-p-toluidinium; iodide | 73637-01-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: tri-N-ethyl-p-toluidinium; iodide
• 英文别名: Tri-N-aethyl-p-toluidinium; Jodid；AMMONIUM, (p-TOLYL)TRIETHYL-, IODIDE；triethyl-(4-methylphenyl)azanium;iodide
• CAS: 73637-01-1
• 化学式: C₁₃H₂₂N*I
• 分子量: 319.229
• InChiKey: RBRVDWQFKIDKOE-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  0.37
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  N,N-二乙基对甲苯胺 、 碘乙烷 生成 tri-N-ethyl-p-toluidinium; iodide
  参考文献：
  名称：

  Schmidt, Journal fur praktische Chemie (Leipzig 1954), 1893, vol. <2> 48, p. 49

  摘要：

  DOI：

文献信息

• Influence of Positively-Charged Guests on the Superoxide Dismutase Mimetic Activity of Copper(II) β-Cyclodextrin Dithiocarbamates¹
  作者：Alex Fragoso、Roberto Cao、Valerian T. D'Souza

  DOI：10.1080/07328309708006519

  日期：1997.2

  The superoxide dismutase (SOD) activity of the Cu(II) complexes of two dithiocarbamate derivatives of cyclodextrin (Cu-C6DTC, Cu-C2DTC), one on the primary (C6DTC) and the other on the secondary (C2DTC) side, was determined in the presence of positively-charged guests which have the general formula RNX(3)(+) (where R = C6H11, X = CH3 (3); R = C6H11, X = C2H5 (4); R = p-CH3C6H4, X = CH3 (5) and R = p-CH3C6H4, X = C2H5 (6). The catalytic activity of both Cu-C2DTC and Cu-C6DTC was enhanced 35-70 % by 3-6 for concentrations of the host equivalent to the IC50 value of the complex. A correlation was found between the net positive charge of the nitrogen atom and the maximum acceleration attained by both complexes. The formation of an inclusion complex between these cationic guests and the CD moiety of these complexes is proposed to be the determining factor in the observed increase in the catalytic activity.
• Schmidt, Journal fur praktische Chemie (Leipzig 1954), 1893, vol. <2> 48, p. 49
  作者：Schmidt

  DOI：——

  日期：——