苯基苯并咪唑磺酸钠 | 5997-53-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 中文名称: 苯基苯并咪唑磺酸钠
• CAS: 5997-53-5
• 化学式: C13H10N2NaO3S
• 分子量: 297.29
• InChiKey: JANTVCOSYRGMDW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  91.4
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Long wavelength ultraviolet ray absorber
  申请人：Kao Corporation

  公开号：EP0154928A2

  公开（公告）日：1985-09-18

  A composition for application to the skin to protect the skin from the long wavelength ultraviolet ray comprises a dibenzoylmethane derivative of the following general formula in which X represents a hydrogen atom, a monovalent metal cation, an organic cation, a linear or branched alkyl group having from 1 to 24 carbon atoms, or a polyoxyalkylene oxide having 2 or 3 carbon atoms, each Y and each Z independently represent a hydroxyl group, a linear or branched alkyl group having from 1 to 24 carbon atoms, or an alkoxy group having from 1 to 24 carbon atoms, or a polyoxyalkylene oxide group having from 2 to 3 carbon atoms, and m and n are independently an integer of from 0 to 3. The composition is adjustable so as to have an optimum HLB balance and has good compatibility with various cosmetic bases. Further, it does not irritate the skin, is difficult to be percutaneously absorbed and shows continued skin-protecting effects.

  一种应用于皮肤以保护皮肤免受长波紫外线伤害的组合物包括通式如下的二苯甲酰甲烷衍生物 其中 X 代表氢原子、一价金属阳离子、有机阳离子、具有 1 至 24 个碳原子的直 链或支链烷基或具有 2 或 3 个碳原子的聚氧化烯；每个 Y 和每个 Z 独立地代表羟基、具有 1 至 24 个碳原子的直链或支链烷基或具有 1 至 24 个碳原子的烷氧基或具有 2 至 3 个碳原子的聚氧化烯；m 和 n 独立地为 0 至 3 的整数。 该组合物可以调节，以达到最佳的 HLB 平衡，并与各种化妆品基质具有良好的兼容性。此外，它不会刺激皮肤，不易被皮下吸收，并具有持续的皮肤保护效果。
• Long wavelength UV ray absorber, process for preparing the same, and cosmetic containing the same
  申请人：KAO CORPORATION

  公开号：EP0303995A1

  公开（公告）日：1989-02-22

  A long wavelength UV ray absorber and a cosmetic comprising the same is disclosed. The long wavelength UV ray absorber comprises (a) a dibenzoylmethane derivative of the type in which the benzene ring of the dibenzoylmethane has a carboxylic acid group, a carboxylate group, or a carboxylic acid ester group, and (b) a polyvalent metal oxide. The long wavelength UV ray absorber can effectively shut out UV-A which is harmful to the skin, thus protecting it from the UV-A. It is stable against light and heat over a long period of time. Since it is sparingly soluble into water, organic solvents, oily substances, or sabum, it is hardly absorbed through the skin and hardly removed from the skin by water or sweat.

  本发明公开了一种长波长紫外线吸收剂和含有该吸收剂的化妆品。长波紫外线吸收剂包括：(a) 二苯甲酰甲烷衍生物，其中二苯甲酰甲烷的苯环具有羧酸基、羧酸基或羧酸酯基；(b) 多价金属氧化物。长波长紫外线吸收剂能有效隔绝对皮肤有害的紫外线 A，从而保护皮肤不受紫外线 A 的伤害。它对光和热具有长期的稳定性。由于它很少溶于水、有机溶剂、油性物质或沙比利，因此很难被皮肤吸收，也很难被水或汗水从皮肤上清除。
• Novel aroyl ketone derivative, UV ray absorber comprising the same, and cosmetic composition containing the same
  申请人：KAO CORPORATION

  公开号：EP0416564A2

  公开（公告）日：1991-03-13

  A novel aroyl ketone derivative represented by formula (I) is disclosed. Ar(COCH₂COR¹)n      (I) wherein R¹ represents a saturated or unsaturated hydrocarbon group having 1-24 carbon atoms, or a linear or branched alkoxyalkyl or alkenyloxyalkyl group having 1-24 carbon atoms, dialkylamino group having 1-24 carbon atoms, Ar represents a benzene or naphthalene ring which may be substituted with one or more hydroxyl groups, alkoxy groups having 1-24 carbon atoms, alkenyloxy groups having 1-24 carbon atoms, polyoxyleneoxy groups, or α-­methylenedioxy groups, and n denotes an integer of 1-4. An UV-ray absorber and cosmetic composition comprising the aroyl ketone derivative of formula (I) are also disclosed. Aroyl ketone derivative (I) of the present invention can provide an excellent UV-ray absorbing effect and has outstanding stability against light, and the UV-ray absorber or cosmetic composition containing the aroyl ketone derivative (I) can exhibit an excellent sunscreening effect.

  本发明公开了一种由式(I)代表的新型芳基酮衍生物。 Ar(COCH₂COR¹)n (I) 其中 R¹ 代表具有 1-24 个碳原子的饱和或不饱和烃基，或具有 1-24 个碳原子的直链或支链烷氧基或烯氧基烷基，具有 1-24 个碳原子的二烷基氨基，Ar 代表可被一个或多个羟基、具有 1-24 个碳原子的烷氧基、具有 1-24 个碳原子的烯氧基、聚氧乙烯氧基或 α-亚甲二氧基取代的苯环或萘环，n 表示 1-4 的整数。此外，还公开了一种紫外线吸收剂和包含式（I）丙酮衍生物的化妆品组合物。本发明的芳基酮衍生物（I）可提供优异的紫外线吸收效果，并具有出色的耐光稳定性，含有该芳基酮衍生物（I）的紫外线吸收剂或化妆品组合物可表现出优异的防晒效果。
• 4,4-Dimethyl-1-phenylpentane-1,3-dione derivative and UV ray absorbent and cosmetic containing the same
  申请人：KAO CORPORATION

  公开号：EP0504844A2

  公开（公告）日：1992-09-23

  A 4,4-Dimethyl-1-phenylpentane-1,3-dione derivatives represented by the following formula (1): wherein all symbols are defined in the disclosure, is disclosed. An ultraviolet ray absorbent and a cosmetic comprising the derivative are also disclosed. The derivative of the present invention have excellent ultraviolet ray absorbing performance and superior light stability, and the ultraviolet ray absorbent and cosmetic comprising the derivative have excellent effect to prevent sunburn.

  由下式（1）代表的 4,4-二甲基-1-苯基-1,3-戊二衍生物： 其中所有符号均在本公开中定义。本发明还公开了一种紫外线吸收剂和一种含有该衍生物的化妆品。本发明的衍生物具有极佳的紫外线吸收性能和优异的光稳定性，包含该衍生物的紫外线吸收剂和化妆品具有极佳的防晒效果。
• Naphthalenmethylenemalonic diesters, and UV absorbers and cosmetic compositions containing the diesters
  申请人：Kao Corporation

  公开号：EP0663206A1

  公开（公告）日：1995-07-19

  The invention relates to UV absorbers and cosmetic compositions containing a naphthalenemethylenemalonic diester represented by the following formula (1): wherein NAP represents a naphthalene group which may optionally have a substituent, and R¹ and R² each independently represent a hydrocarbon group, an alkoxyalkyl group, or an alkoxyalkylenoxyalkyl group. The UV absorbers and the cosmetic compositions of the invention exhibit excellent ultraviolet ray absorbing action, and are stable to light.

  本发明涉及含有下式（1）所代表的萘亚甲基丙二酸二酯的紫外线吸收剂和化妆品组合物： 其中，NAP 代表萘基，该萘基可选择性地具有一个取代基；R¹ 和 R² 各自独立地代表烃基、烷氧基烷基或烷氧基烯氧基烷基。本发明的紫外线吸收剂和化妆品组合物具有优异的紫外线吸收作用，并且对光稳定。