1,8-Dimethylene-1,2,3,4,5,6,7,8-octahydro-anthracene | 864851-82-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 1,8-Dimethylene-1,2,3,4,5,6,7,8-octahydro-anthracene
• 英文别名: 4,5-Dimethylidene-1,2,3,6,7,8-hexahydroanthracene；4,5-dimethylidene-1,2,3,6,7,8-hexahydroanthracene
• CAS: 864851-82-1
• 化学式: C₁₆H₁₈
• 分子量: 210.319
• InChiKey: MPBGLCCMUOLFST-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  16
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1,8-Dimethylene-1,2,3,4,5,6,7,8-octahydro-anthracene 、 二碘甲烷 在 diethylzinc 作用下， 以24%的产率得到2',3',4',5',6',7'-hexahydrodispiro[cyclopropane-1,1'-anthracene-8',1''-cyclopropane]
  参考文献：
  名称：

  A hydrogen atom sandwiched by cyclopropanes

  摘要：

  2',3',4',5',6',7'-Hexahydrodispiro[cyclopropane-1,1 '-anthracene-8',1"-eyelopropane] (1) was prepared by double olefination (Wittig) and double methylenation (Furukawa) of 1,8-dioxo- 1,2,3,4,5,6,7,8 - octahydroanthracene (4) that was in turn prepared in two steps from 1,3-dibromobenzene. The X-ray structure of 1 shows that the C-9-H of its anthracene core is located 2.6 angstrom from the centroids of each of the flanking cyclopropane rings. The H-1 NMR spectrum of 1 shows that the C-9-H resonance (delta 5.95) falls 0.84 ppm upfield from the C-10-H resonance (delta 6.79). (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2005.07.097
• 作为产物：
  描述：

  Dimethyl-m-benzoldibutanat 在 氢氧化钾 作用下， 以 水 为溶剂， 生成 1,8-Dimethylene-1,2,3,4,5,6,7,8-octahydro-anthracene
  参考文献：
  名称：

  A hydrogen atom sandwiched by cyclopropanes

  摘要：

  2',3',4',5',6',7'-Hexahydrodispiro[cyclopropane-1,1 '-anthracene-8',1"-eyelopropane] (1) was prepared by double olefination (Wittig) and double methylenation (Furukawa) of 1,8-dioxo- 1,2,3,4,5,6,7,8 - octahydroanthracene (4) that was in turn prepared in two steps from 1,3-dibromobenzene. The X-ray structure of 1 shows that the C-9-H of its anthracene core is located 2.6 angstrom from the centroids of each of the flanking cyclopropane rings. The H-1 NMR spectrum of 1 shows that the C-9-H resonance (delta 5.95) falls 0.84 ppm upfield from the C-10-H resonance (delta 6.79). (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2005.07.097

文献信息

• A hydrogen atom sandwiched by cyclopropanes
  作者：Robert S. Walters、Douglas M. Ho、Robert A. Pascal

  DOI：10.1016/j.tetlet.2005.07.097

  日期：2005.9

  2',3',4',5',6',7'-Hexahydrodispiro[cyclopropane-1,1 '-anthracene-8',1"-eyelopropane] (1) was prepared by double olefination (Wittig) and double methylenation (Furukawa) of 1,8-dioxo- 1,2,3,4,5,6,7,8 - octahydroanthracene (4) that was in turn prepared in two steps from 1,3-dibromobenzene. The X-ray structure of 1 shows that the C-9-H of its anthracene core is located 2.6 angstrom from the centroids of each of the flanking cyclopropane rings. The H-1 NMR spectrum of 1 shows that the C-9-H resonance (delta 5.95) falls 0.84 ppm upfield from the C-10-H resonance (delta 6.79). (c) 2005 Elsevier Ltd. All rights reserved.