1,2-bis[4-(N-hydroxy-tert-butylamino)phenyl]-1,1,2,2-tetramethyldisilane | 402588-64-1

• 分子结构分类: 有机化合物 - 苯类化合物 - N-苯基羟胺
• 英文名称: 1,2-bis[4-(N-hydroxy-tert-butylamino)phenyl]-1,1,2,2-tetramethyldisilane
• 英文别名: 1,2-bis[4-(N-hydroxy-t-butylamino)phenyl]-1,1,2,2-tetramethyl-disilane；N-tert-butyl-N-[4-[[[4-[tert-butyl(hydroxy)amino]phenyl]-dimethylsilyl]-dimethylsilyl]phenyl]hydroxylamine
• CAS: 402588-64-1
• 化学式: C₂₄H₄₀N₂O₂Si₂
• 分子量: 444.765
• InChiKey: SWAVLNSMRMIDFQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.28
• 重原子数：
  30
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  46.9
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1,2-bis[4-(N-hydroxy-tert-butylamino)phenyl]-1,1,2,2-tetramethyldisilane 在 silver(l) oxide 作用下， 以 乙醚 为溶剂， 反应 0.5h， 以68%的产率得到1,2-bis[4-(N-oxy-tert-butylamino)phenyl]-1,1,2,2-tetramethyldisilane
  参考文献：
  名称：

  Synthesis of Phenylnitroxides Bridged by an sp³-Linkage

  摘要：

  Silicon- and carbon-bridged phenylnitroxides were synthesized. They exhibited similar ESR profiles independent of the nature of the sp(3) bridge and the substitution mode of the phenylene units. The spectra revealed a quintet signal at room temperature, which became a broad triplet by lowering the temperature. Accumulated ESR measurements at 77 K led to the successful observation of a signal at Deltam(s) = 2, indicating that the triplet state was involved in this system.

  DOI：

  10.1021/ol017093p
• 作为产物：
  描述：

  tert-butylnitroso dimer 、 1,2-bis(4-bromophenyl)-1,1,2,2-tetramethyldisilane 在 正丁基锂 作用下， 以 乙醚 、 正己烷 、 四氢呋喃 为溶剂， 反应 1.0h， 以18%的产率得到1,2-bis[4-(N-hydroxy-tert-butylamino)phenyl]-1,1,2,2-tetramethyldisilane
  参考文献：
  名称：

  Synthesis of Phenylnitroxides Bridged by an sp³-Linkage

  摘要：

  Silicon- and carbon-bridged phenylnitroxides were synthesized. They exhibited similar ESR profiles independent of the nature of the sp(3) bridge and the substitution mode of the phenylene units. The spectra revealed a quintet signal at room temperature, which became a broad triplet by lowering the temperature. Accumulated ESR measurements at 77 K led to the successful observation of a signal at Deltam(s) = 2, indicating that the triplet state was involved in this system.

  DOI：

  10.1021/ol017093p

文献信息

• Synthesis of Phenylnitroxides Bridged by an sp³-Linkage
  作者：Joji Ohshita、Toshiyuki Iida、Nobuaki Ohta、Kenji Komaguchi、Masaru Shiotani、Atsutaka Kunai

  DOI：10.1021/ol017093p

  日期：2002.2.1

  Silicon- and carbon-bridged phenylnitroxides were synthesized. They exhibited similar ESR profiles independent of the nature of the sp(3) bridge and the substitution mode of the phenylene units. The spectra revealed a quintet signal at room temperature, which became a broad triplet by lowering the temperature. Accumulated ESR measurements at 77 K led to the successful observation of a signal at Deltam(s) = 2, indicating that the triplet state was involved in this system.