2-(羟氨基)苯酚 | 91367-87-2

• 分子结构分类: 有机化合物 - 苯类化合物 - N-苯基羟胺
• 中文名称: 2-(羟氨基)苯酚
• 英文名称: 2-(hydroxyamino)phenyl alcohol
• 英文别名: o-hydroxylaminophenol；(hydroxyamino)phenol；2-hydroxyaminophenol；o-hydroxyaminophenol；hydroxylaminophenol；oxyaminophenol；oxylanilinol；2-(Hydroxyamino)phenol
• CAS: 91367-87-2
• 化学式: C₆H₇NO₂
• 分子量: 125.127
• InChiKey: UYPGGNLSLMOLMU-UHFFFAOYSA-N

物化性质

• 沸点：
  267.3±42.0 °C(Predicted)
• 密度：
  1.416±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  9
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  52.5
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-(羟氨基)苯酚 在 Britton-Robbinson buffer 、 Triton X-100 作用下， 以 乙醇 为溶剂， 生成 2-氨基苯酚
  参考文献：
  名称：

  Singh, M.; Chandra, K., Zeitschrift fur Physikalische Chemie (Leipzig), 1984, vol. 265, # 5, p. 977 - 989

  摘要：

  DOI：
• 作为产物：
  描述：

  硝苯酚 在 Britton-Robbinson buffer 、 sodium dodecyl-sulfate 作用下， 以 乙醇 为溶剂， 生成 2-(羟氨基)苯酚
  参考文献：
  名称：

  Singh, M.; Chandra, K., Zeitschrift fur Physikalische Chemie (Leipzig), 1984, vol. 265, # 5, p. 977 - 989

  摘要：

  DOI：

文献信息

• A new route to the synthesis of isoxazoline derivatives from dihydropyran via cycloaddition reaction in ionic liquid
  作者：Bhaskar Chakraborty、Chiran Devi Sharma

  DOI：10.1016/j.tetlet.2013.07.159

  日期：2013.10

  A new approach to the synthesis and 1,3-dipolar cycloadditions of nitrones has been described from 2,3-dihydro-4H-pyran and various hydroxylamines, with electron-deficient alkynes for the synthesis of isoxazoline derivatives. Significant rate acceleration and improved yields of exclusively exo isoxazolines in 1-butyl-3-methylimidazolium based ionic liquids have been observed. Novel isoxazolines may

  已经描述了由2，3-二氢-4 H-吡喃和各种羟胺与电子不足的炔烃合成异恶唑啉衍生物的新的合成和1,3-偶极环加成硝基的新方法。显著速率加速和改善的产率仅仅外切在1-丁基-3-甲基咪唑鎓类离子液体异恶唑啉已经观察到。新型异恶唑啉可用作合成各种肽的前体。
• Process for preparing ortho substituted phenylamines
  申请人：——

  公开号：US20040162444A1

  公开（公告）日：2004-08-19

  A process is disclosed for preparing ortho substituted phenylamines comprising contacting phenylhydroxylamine, optionally substituted with at least one inert substituent, with a nucleophilic reagent in the presence of a manganese oxide at a temperature between about 10° C. and about 170° C. and a pressure from subatmospheric to superatmospheric such that an ortho substituted phenylamine, optionally correspondingly substituted with at least one inert substituent, is predominantly formed.

  一种制备邻位取代苯胺的方法被披露，包括将苯基羟胺与一种亲核试剂接触，所述苯基羟胺可以选择性地被至少一种惰性取代基取代，并在存在锰氧化物的条件下，在温度约为10℃到170℃之间以亚大气压到超大气压的压力下进行反应，从而主要形成一种邻位取代苯胺，该苯胺可以选择性地相应地被至少一种惰性取代基取代。
• METHODS FOR MEASUREMENT OF CALCIUM IONS
  申请人：Roche Diagnostics Operations, Inc.

  公开号：US20130023055A1

  公开（公告）日：2013-01-24

  Reagents and methods for determination of calcium within a sample. Specific embodiments include a reagent for determination of calcium comprising a mono-nitro substituted BAPTA-type chelator (BAPTA=1,2-bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid). Methods for accurate determination of calcium in a sample, such as a blood, whole blood, plasma or serum or any other aqueous liquid sample including cerebrospinal fluid, lymph, salivary juice or urine. Embodiments are also useful for clinical diagnoses.

  本发明涉及用于测定样品中钙的试剂和方法。具体实施例包括用于测定钙的试剂，其中包括一种单硝基取代的BAPTA型螯合剂（BAPTA=1,2-双（2-氨基苯氧基）乙烷-N，N，N'，N'-四乙酸）。本发明还涉及用于准确测定样品中钙的方法，例如血液、全血、血浆或血清或任何其他水性液体样品，包括脑脊液、淋巴、唾液或尿液。该实施例还有助于临床诊断。
• ANTICANCER COMPOSITIONS
  申请人：Orient Cancer Therapy Co. Ltd

  公开号：EP1266661A1

  公开（公告）日：2002-12-18

  An ink composition comprising at least one triarylmethane-based dye as a coloring material, an alcohol having 2 or more carbon atoms, a polyhydric alcohol or a glycol ether as a solvent, and a resin which can dissolve in the solvent, the triarylmethane-based dye comprising a compound represented by the following formula: [C(-Ar-Y)3]A wherein each Ar is independently an aryl group substituted, or not substituted, by a halogen or an alkyl group, each Y is independently a diethylamino group or hydrogen, provided that at least two Y are a diethylamino group, A is a halogen or an organic acid group, and A is charge-balanced to the residue.

  一种墨水组合物，包括至少一种作为着色材料的三芳基甲烷基染料、一种具有 2 个或更多碳原子的醇、一种作为溶剂的多元醇或乙二醇醚以及一种可溶于溶剂的树脂，所述三芳基甲烷基染料包括下式所代表的化合物：[C(-Ar-Y)3]A 其中每个 Ar 独立地为被卤素或烷基取代或未被卤素或烷基取代的芳基，每个 Y 独立地为二乙氨基或氢，但至少有两个 Y 为二乙氨基，A 为卤素或有机酸基，且 A 与残基电荷平衡。
• OIL-BASE INK COMPOSITION, WRITING UTENSILS AND DYES TO BE USED THEREIN
  申请人：MITSUBISHI PENCIL Co., Ltd.

  公开号：EP1266940A9

  公开（公告）日：2003-03-05

  An ink composition comprising at least one triarylmethane-based dye as a coloring material, an alcohol having 2 or more carbon atoms, a polyhydric alcohol or a glycol ether as a solvent, and a resin which can dissolve in the solvent, the triarylmethane-based dye comprising a compound represented by the following formula: [C(-Ar-Y)3]A wherein each Ar is independently an aryl group substituted, or not substituted, by a halogen or an alkyl group, each Y is independently a diethylamino group or hydrogen, provided that at least two Y are a diethylamino group, A is a halogen or an organic acid group, and A is charge-balanced to the residue.

  一种墨水组合物，包括至少一种作为着色材料的三芳基甲烷基染料、一种具有 2 个或更多碳原子的醇、一种作为溶剂的多元醇或乙二醇醚以及一种可溶于溶剂的树脂，所述三芳基甲烷基染料包括下式所代表的化合物：[C(-Ar-Y)3]A 其中每个 Ar 独立地为被卤素或烷基取代或未被卤素或烷基取代的芳基，每个 Y 独立地为二乙氨基或氢，但至少有两个 Y 为二乙氨基，A 为卤素或有机酸基，且 A 与残基电荷平衡。