[Ethoxy(phenyl)phosphoryl]-(4-methylphenyl)methanone | 1207386-94-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: [Ethoxy(phenyl)phosphoryl]-(4-methylphenyl)methanone
• CAS: 1207386-94-4
• 化学式: C₁₆H₁₇O₃P
• 分子量: 288.283
• InChiKey: UWMRIAVKTXAJHF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  [Ethoxy(phenyl)phosphoryl]-(4-methylphenyl)methanone 、 丙酮 在 L-脯氨酸 、 水 作用下， 反应 120.0h， 生成 ethyl [1-hydroxy-1-(4-methylphenyl)-3-oxobutyl](phenyl)phosphinate 、 ethyl [1-hydroxy-1-(4-methylphenyl)-3-oxobutyl](phenyl)phosphinate 、 ethyl [1-hydroxy-1-(4-methylphenyl)-3-oxobutyl](phenyl)phosphinate
  参考文献：
  名称：

  Organocatalytic Enantioselective Synthesis of Both Diastereomers of α-Hydroxyphosphinates

  摘要：

  Racemic alpha-acylphosphinates and formylphosphinate hydrate were used directly as the substrates in a proline derivative-catalyzed cross aldol reaction with ketones. Because of the preexisting phosphorus stereogenic center, a mixture of two diastereomers of the corresponding alpha-hydroxyphosphinates was obtained in this reaction. Good to high enantioselectivities (up to 99% ee) were obtained simultaneously for the two diastereomers in good yields. Good diastereoselectivities were also obtained when the reaction generates an additional carbon stereogenic center.

  DOI：

  10.1021/jo9022099

文献信息

• OPTICAL RECORDING COMPOSITION AND HOLOGRAPHIC RECORDING MEDIUM
  申请人：YAMADA Satoru

  公开号：US20090142671A1

  公开（公告）日：2009-06-04

  The present invention provides an optical recording composition comprising a compound denoted by general formula (I) and a holographic recording medium comprising a recording layer, wherein the recording layer comprises a compound denoted by general formula (I). In general formula (I), R 1 denotes a hydrogen atom or an alkyl group, and Z 1 denotes an atom group, the atom group forming a ring structure with a sulfur atom and a carbon atom which are adjacent to the atom group, and a carbon atom bonded to the sulfur atom.
• HOLOGRAPHIC RECORDING COMPOSITION AND HOLOGRAPHIC RECORDING MEDIUM
  申请人：YAMADA Satoru

  公开号：US20090170009A1

  公开（公告）日：2009-07-02

  The present invention provides a holographic recording composition comprising a compound denoted by general formula (I) and a holographic recording medium comprising a recording layer, wherein the recording layer comprises a compound denoted by general formula (I). In general formula (I), R 1 denotes a hydrogen atom or a substituent having a Hammett value, σp, of equal to or greater than −0.30, each of R 2 , R 3 , R 4 , R 5 , and R 6 independently denotes a hydrogen atom or a substituent, each of A and B independently denotes a substituent and a combination of A and B is (cyano group, cyano group), (oxycarbonyl group, oxycarbonyl group), (acyl group, acyl group), (sulfonyl group, sulfonyl group), (cyano group, acyl group), (cyano group, sulfonyl group), (oxycarbonyl group, acyl group), (oxycarbonyl group, sulfonyl group), or (sulfonyl group, acyl group), and at least one of R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , A, and B comprises a polymerizable group.
• CURABLE RESIN COMPOSITION FOR CEMENTED LENS, IMAGING LENS, AND METHOD FOR MANUFACTURING IMAGING LENS
  申请人：Yamada Satoru

  公开号：US20120019938A1

  公开（公告）日：2012-01-26

  A curable resin composition for a cemented lens capable of manufacturing a cemented lens excellent in heat resistance in reflowing treatment at a temperature of 260° C. or higher and adhesion between lenses, and capable of reducing manufacturing costs of lenses and capable of lightening lenses, is provided. The curable resin composition for a cemented lens includes: (a) a compound represented by the following formula (I); and (b) a radical polymerization initiator. wherein R 1 represents a hydrogen atom or an alkyl group; and Z 1 represents a cyclic structure together with two carbon atoms and a sulfur atom.
• Organocatalytic Enantioselective Synthesis of Both Diastereomers of α-Hydroxyphosphinates
  作者：Sampak Samanta、Sandun Perera、Cong-Gui Zhao

  DOI：10.1021/jo9022099

  日期：2010.2.19

  Racemic alpha-acylphosphinates and formylphosphinate hydrate were used directly as the substrates in a proline derivative-catalyzed cross aldol reaction with ketones. Because of the preexisting phosphorus stereogenic center, a mixture of two diastereomers of the corresponding alpha-hydroxyphosphinates was obtained in this reaction. Good to high enantioselectivities (up to 99% ee) were obtained simultaneously for the two diastereomers in good yields. Good diastereoselectivities were also obtained when the reaction generates an additional carbon stereogenic center.