N,N-Dibenzyl-2-methoxyethylamin | 57619-22-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N,N-Dibenzyl-2-methoxyethylamin
• 英文别名: dibenzyl-(2-methoxy-ethyl)-amine；Dibenzyl-(2-methoxy-aethyl)-amin；N,N-dibenzyl-2-methoxyethanamine
• CAS: 57619-22-4
• 化学式: C₁₇H₂₁NO
• mdl: MFCD02026411
• 分子量: 255.36
• InChiKey: YSTZKDDIZBCQRY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  19
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.294
• 拓扑面积：
  12.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  地苯那明 、 sodium methylate 在 甲醇 作用下， 生成 N,N-Dibenzyl-2-methoxyethylamin
  参考文献：
  名称：

  β-Dialkylaminoethyl Esters with Adrenergic Blocking Activity

  摘要：

  DOI：

  10.1021/ja01133a028

文献信息

• Mild and efficient capture and functionalisation of CO2 using silver(i) oxide and application to 13C-labelled dialkyl carbonates
  作者：Gemma A. Tunbridge、Riccardo Baruchello、Lorenzo Caggiano

  DOI：10.1039/c3ra23281f

  日期：——

  A high yielding three-component reaction between β-iodo ethylamine derivatives, MeOH and gaseous CO2 at ambient temperatures and pressures is reported using silver(I) oxide. Unfunctionalised alkyl iodides were also found to be effective in this transformation and their optimisation is also described. To highlight the ease and control with which gaseous CO2 can be captured and functionalised under mild conditions, the reaction was performed using 13C-enriched CO2 to afford specifically 13C-carbonyl-labelled dialkyl carbonates with exquisite control of the isotopic purity in good yields and without the need for specialised equipment.

  报道了一种高产率的三组分反应，涉及β-碘乙胺衍生物、甲醇和在常温常压下的气态二氧化碳，使用氧化银（I）作为催化剂。未官能化的烷基碘化物也被发现在此转化中有效，并且也描述了它们的优化。为了突出在温和条件下捕获和官能化气态二氧化碳的简便性和控制性，该反应采用13C标记的二氧化碳进行，从而在无需特殊设备的情况下，以良好产率和精细控制的同位素纯度得到特异的13C-羰基标记的二烷基碳酸酯。
• HYBRID BLOCK COPOLYMER MICELLES WITH MIXED STEREOCHEMISTRY FOR ENCAPSULATION OF HYDROPHOBIC AGENTS
  申请人：Intezyne Technologies, Inc.

  公开号：US20150232616A1

  公开（公告）日：2015-08-20

  The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.

  本发明涉及聚合物化学领域，更具体地涉及多嵌段共聚物及包含其的胶束。
• Hydrophobically modified alkylene oxide urethane polymer
  申请人：Rohm and Haas Company

  公开号：EP2455412A1

  公开（公告）日：2012-05-23

  The present invention relates to a composition comprising a hydrophobically modified alkylene oxide urethane polymer with pendant or end-capping tertiary amine groups, the conjugate acids of which have a pKa in the range of about 4.5 to about 6.5. The composition of the present invention is useful as a rheology modifier for paint formulations formulated over a wide pH range and is more stable to heat aging than higher pKa amine-modified HEURs.

  本发明涉及一种组合物，该组合物包含一种疏水改性的环氧亚烷基聚氨酯聚合物，该聚合物具有悬垂或端封的叔胺基团，其共轭酸的 pKa 值在约 4.5 至约 6.5 之间。本发明的组合物可用作涂料配方的流变改性剂，适用于较宽的 pH 值范围，与 pKa 值较高的胺改性 HEUR 相比，本发明的组合物对热老化更稳定。
• SYNTHESIS OF HYBRID BLOCK COPOLYMERS AND USES THEREOF
  申请人：Breitenkamp Kurt

  公开号：US20110021718A1

  公开（公告）日：2011-01-27

  The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and methods of preparing the same.
• AZIDE FUNCTIONALIZED PEPTIDE TARGETING GROUPS
  申请人：Breitenkamp Kurt

  公开号：US20110092668A1

  公开（公告）日：2011-04-21

  The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.