Malonamicacid,p-menth-3-ylester,(?脿)-(8CI) | 6129-88-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: Malonamicacid,p-menth-3-ylester,(?脿)-(8CI)
• 英文名称: 2-[1-[2-[4-[(4-Nitrophenyl)methyl]pyridin-1-ium-1-yl]ethyl]pyridin-1-ium-4-yl]ethanesulfonate
• CAS: 6129-88-0
• 化学式: C21H22N3O5S+
• 分子量: 428.5
• InChiKey: XAGWXSOKYCIUFX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  30
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  119
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• Cooling composition comprising trimethyl isopropyl butanamide
  申请人：Kraft Foods Global Brands LLC

  公开号：EP2559424A1

  公开（公告）日：2013-02-20

  This description provides cooling compositions that deliver a prolonged physiological cooling sensation to the skin or a mucous membrane. The cooling compositions may be present alone or in product such as a chewing gum or a confection. The cooling compositions comprise a menthyl ester and a second cooling agent, which may be WS-3 or WS-23 and optionally menthol. The menthyl ester may be a menthyl glutarate or a menthyl succinate ester, and it may be present in an amount of at least 5 weight percentage, at least 10 weight percentage, at least 20 weight percentage, at least 30 weight percentage, or at least 40 weight percentage. In many instances, the menthyl ester is present in an amount of 5 to 60 weight percentage or especially 15 to 50 wt %.

  本说明提供的降温组合物可为皮肤或粘膜带来长时间的生理降温感觉。这种降温组合物可以单独使用，也可以与口香糖或糖果等产品一起使用。降温组合物由薄荷酯和第二种降温剂组成，第二种降温剂可以是 WS-3 或 WS-23，也可以是薄荷醇。薄荷酯可以是戊二酸薄荷酯或琥珀酸薄荷酯，其含量可以是至少 5 重量百分比、至少 10 重量百分比、至少 20 重量百分比、至少 30 重量百分比或至少 40 重量百分比。在许多情况下，薄荷酯的含量为 5 至 60 重量百分比，特别是 15 至 50 重量百分比。
• MENTHYL HALF ACID ESTER DIRIVATIVES, PROCESSES FOR PREPARING SAME, AND USES THEREOF FOR THEIR COOLING/REFRESHING EFFECT IN CONSUMABLE MATERIALS
  申请人：Dewis L. Mark

  公开号：US20050004214A1

  公开（公告）日：2005-01-06

  Described is a genus of menthyl half acid ester derivatives having the structure: and processes for producing same, wherein n is an integer of from 1 to 5; wherein X is either —OR″ or —NRR′; wherein R″ is hydrogen, C 1 -C 5 lower alkyl or C 3 -C 6 lower alkenyl; wherein R is hydrogen, C 1 -C 5 lower alkyl, 2-hydroxyethyl or cyclopropyl and wherein R′ is hydrogen, methyl or ethyl; with the proviso that when X is —OR″, n is an integer of from 3 to 5, having utility for augmenting, enhancing or imparting a taste or cooling effect or refreshing effect in or to an ingestible or topical composition.

  描述了具有以下结构的薄荷半酸酯衍生物属： 及其生产工艺，其中 n 是 1 至 5 的整数；其中 X 是-OR″或-NRR′；其中 R″ 是氢、C 1 -C 5 低级烷基或 C 3 -C 6 低级烯基；其中 R 是氢、C 1 -C 5 低级烷基、2-羟乙基或环丙基，其中 R′为氢、甲基或乙基；但当 X 为-OR″时，n 为 3 至 5 的整数。
• Monomenthyl ester derivatives of dicarboxylic acids, processes for preparing same, and uses thereof for their cooling/refreshing effect in consumable materials
  申请人：INTERNATIONAL FLAVORS & FRAGRANCES INC.

  公开号：EP1493336B1

  公开（公告）日：2009-02-25
• Cooling compositions
  申请人：Kiefer Jesse

  公开号：US20070077331A1

  公开（公告）日：2007-04-05

  This description provides cooling compositions that deliver a prolonged physiological cooling sensation to the skin or a mucous membrane. The cooling compositions may be present alone or in product such as a chewing gum or a confection. The cooling compositions comprise a menthyl ester and a second cooling agent, which may be WS-3 or WS-23 and optionally menthol. The menthyl ester may be a menthyl glutarate or a menthyl succinate ester, and it may be present in an amount of at least 5 weight percentage, at least 10 weight percentage, at least 20 weight percentage, at least 30 weight percentage, or at least 40 weight percentage. In many instances, the menthyl ester is present in an amount of 5 to 60 weight percentage or especially 15 to 50 wt %.
• Cooling compositions including menthyl esters
  申请人：Kiefer Jesse

  公开号：US20070221236A1

  公开（公告）日：2007-09-27

  This description provides cooling compositions that deliver a prolonged physiological cooling sensation to the skin or a mucous membrane. The cooling compositions may be present alone or in product such as a chewing gum or a confection. In some embodiments, the cooling compositions include menthyl glutarate and at least one additional cooling agent, which may be WS-3 or WS-23, and optionally menthol. The cooling compositions may be in a liquid form at room temperature.