diethyl 2-(2,2-bis(4-chlorophenyl)vinyl)naphthalene-2,2(1H)-dicarboxylate | 1049796-75-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: diethyl 2-(2,2-bis(4-chlorophenyl)vinyl)naphthalene-2,2(1H)-dicarboxylate
• 英文别名: diethyl 4-[2,2-bis(4-chlorophenyl)ethenyl]-1H-naphthalene-2,2-dicarboxylate
• CAS: 1049796-75-9
• 化学式: C₃₀H₂₆Cl₂O₄
• 分子量: 521.44
• InChiKey: HFIVNQIZIXLALE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.2
• 重原子数：
  36
• 可旋转键数：
  9
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  diethyl 2-benzyl-2-(4-,4-bis(4-chlorophenyl)-4-hydroxybut-2-ynyl)malonate 在 对甲苯磺酸 作用下， 以 硝基甲烷 为溶剂， 以89%的产率得到diethyl 2-(2,2-bis(4-chlorophenyl)vinyl)naphthalene-2,2(1H)-dicarboxylate
  参考文献：
  名称：

  Controllable One-Step Synthesis of Spirocycles, Polycycles, and Di- and Tetrahydronaphthalenes from Aryl-Substituted Propargylic Alcohols

  摘要：

  A novel, convenient, and efficient method has been developed for selective synthesis of spirocycle, polycycle, and di- and tetrahydronaphthalene systems from aryl-substituted propargylic alcohols by FeCl(3)- or TsOH-catalyzed multiple activations of unsaturated C-C bonds and C-H bonds.

  DOI：

  10.1021/jo801210n

文献信息

• Controllable One-Step Synthesis of Spirocycles, Polycycles, and Di- and Tetrahydronaphthalenes from Aryl-Substituted Propargylic Alcohols
  作者：Wen Huang、Pengzhi Zheng、Zhengxing Zhang、Ruiting Liu、Zhenxia Chen、Xigeng Zhou

  DOI：10.1021/jo801210n

  日期：2008.9.1

  A novel, convenient, and efficient method has been developed for selective synthesis of spirocycle, polycycle, and di- and tetrahydronaphthalene systems from aryl-substituted propargylic alcohols by FeCl(3)- or TsOH-catalyzed multiple activations of unsaturated C-C bonds and C-H bonds.