2-(Methoxymethyl)-4,6-bis(4-methylphenyl)-1,3,5-triazine | 1190373-95-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(Methoxymethyl)-4,6-bis(4-methylphenyl)-1,3,5-triazine
• CAS: 1190373-95-5
• 化学式: C₁₉H₁₉N₃O
• 分子量: 305.379
• InChiKey: ILSGCEOHLTYUHZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  47.9
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  N-(1-p-toluoylamino-2,2-dichloroethyl)-4-methylbenzamidine 、 sodium methylate 以 甲醇 为溶剂， 反应 4.0h， 以80%的产率得到2-(Methoxymethyl)-4,6-bis(4-methylphenyl)-1,3,5-triazine
  参考文献：
  名称：

  Cyclocondensation of 2,2-dichloroethenylbenzamide and its analogs with amidines and hydrogen sulfide in the presence of bases

  摘要：

  Available chlorine-containing enamides of the general formula Cl(2)C=CHNHCOR (I) easily react with benzamidine and its derivatives to give 1:1 adducts which under heating with sodium methylate transform to 2-(methoxymethyl)-4,5-diaryl-s-triazines. Reaction of compounds (I) with hydrogen sulfide in the presence of triethylamine yields a mixture of products. Only the corresponding 3,5-bis(acylaminomethyl)-1,2,4-tritiolanes were isolated from the reaction mixture in moderate yield.

  DOI：

  10.1134/s1070363209030268

文献信息

• Cyclocondensation of 2,2-dichloroethenylbenzamide and its analogs with amidines and hydrogen sulfide in the presence of bases
  作者：B. A. Demidchuk、S. O. Seferov、A. N. Vasilenko、V. S. Brovarets、B. S. Drach

  DOI：10.1134/s1070363209030268

  日期：2009.3

  Available chlorine-containing enamides of the general formula Cl(2)C=CHNHCOR (I) easily react with benzamidine and its derivatives to give 1:1 adducts which under heating with sodium methylate transform to 2-(methoxymethyl)-4,5-diaryl-s-triazines. Reaction of compounds (I) with hydrogen sulfide in the presence of triethylamine yields a mixture of products. Only the corresponding 3,5-bis(acylaminomethyl)-1,2,4-tritiolanes were isolated from the reaction mixture in moderate yield.