1-(2-Phenylcyclopropyl)urea | 90917-95-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(2-Phenylcyclopropyl)urea
• 英文别名: (2-phenylcyclopropyl)urea
• CAS: 90917-95-6
• 化学式: C₁₀H₁₂N₂O
• 分子量: 176.21
• InChiKey: AVVMSHVXSGLTEZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  55.1
• 氢给体数：
  2
• 氢受体数：
  1

文献信息

• [EN] DIHYDRO-CYCLOPENTA-ISOQUINOLINE DERIVATIVES<br/>[FR] DÉRIVÉS DE DIHYDRO-CYCLOPENTA-ISOQUINOLINE
  申请人：UCB BIOPHARMA SRL

  公开号：WO2021130255A1

  公开（公告）日：2021-07-01

  The present invention relates to dihydro-cyclopenta-isoquinoline derivatives of formula (I), processes for preparing them, pharmaceutical compositions containing them and their use in treating disorders caused by IgE (such as allergic responses, non-allergic mast cell responses or certain autoimmune responses), and in particular disorders caused by the interaction of IgE with the FcεRI receptor.

  本发明涉及式（I）的二氢环戊基异喹啉衍生物，其制备方法，含有它们的药物组合物以及它们在治疗由IgE引起的疾病（如过敏反应、非过敏肥大细胞反应或某些自身免疫反应）中的用途，特别是由IgE与FcεRI受体相互作用引起的疾病。
• DIHYDRO-CYCLOPENTA-ISOQUINOLINE DERIVATIVES
  申请人：UCB Biopharma SRL

  公开号：EP4081299A1

  公开（公告）日：2022-11-02
• [EN] NOVEL PEPTIDOMIMETIC NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS<br/>[FR] NOUVEAUX INHIBITEURS PEPTIDOMIMETIQUES DE LA SERINE PROTEASE NS3 DU VIRUS DE L'HEPATITE C
  申请人：SCHERING CORP

  公开号：WO2005021584A2

  公开（公告）日：2005-03-10

  The present application discloses a compound, or enantiomers, stereoisomers, rotamers, tautomers or racemates of said compound, or pharmaceutically acceptable salts or solvates of said compound, said compound having the general structure shown in Formula (1): useful in the treatment or prevention or amelioration of one or more symptoms of hepatitis C.