o-Methyl-dithiobenzoesaeure | 53724-30-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: o-Methyl-dithiobenzoesaeure
• 英文别名: 2-methyl-dithiobenzoic acid；2-Methyl-dithiobenzoesaeure；2-Methylbenzenecarbodithioic acid
• CAS: 53724-30-4
• 化学式: C₈H₈S₂
• 分子量: 168.284
• InChiKey: USIVJHOBSRZNIW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  33.1
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  o-Methyl-dithiobenzoesaeure 在 吡啶 、 盐酸羟胺 作用下， 生成 (E)-N-羟基-1-(2-甲基苯基)甲亚胺
  参考文献：
  名称：

  Wuyts, Bulletin des Societes Chimiques Belges, 1930, vol. 39, p. 58,63

  摘要：

  DOI：
• 作为产物：
  描述：

  二硫化碳 、 邻甲苯基溴化镁 在 乙醚 作用下， 生成 o-Methyl-dithiobenzoesaeure
  参考文献：
  名称：

  THE SYNTHESIS OF ALDEHYDES FROM GRIGNARD REAGENTS. II. POLYMETHYLBENZALDEHYDES

  摘要：

  DOI：

  10.1021/jo01204a003

文献信息

• Insecticidal N'-substituted-N-acyl-N'-alkylcarbonylhydrazines
  申请人：ROHM AND HAAS COMPANY

  公开号：EP0234944A1

  公开（公告）日：1987-09-02

  This invention relates to certain insecticidal N'- substituted-N-acyl-N'-alkylcarbonylhydrazines, compositions containing them and the use of the compounds and compositions as insecticides, especially against insects from the order Lepidoptera and Coleoptera.

  本发明涉及某些杀虫的 N'-取代-N-酰基-N'-烷基羰基肼、含有这些化合物的组合物以及这些化合物和组合物作为杀虫剂的用途，特别是针对鳞翅目和鞘翅目昆虫的用途。
• [DE] PEPTIDE ALS DIAGNOSTIKUM UND THERAPEUTIKUM FÜR AUTOIMMUNERKRANKUNGEN<br/>[EN] PEPTIDE AS DIAGNOSTIC AND THERAPEUTIC AGENT FOR AUTOIMMUNE DISEASES<br/>[FR] PEPTIDES SERVANT D'AGENT DIAGNOSTIQUE ET D'AGENT THERAPEUTIQUE POUR LES MALADIES AUTO-IMMUNES
  申请人：WILDNER, Gerhild

  公开号：WO1998012221A1

  公开（公告）日：1998-03-26

  (DE) Die Erfindung betrifft von den $g(a)1- oder $g(a)2-Domänen von HLA-B27 bzw. humanem Keratin VI abgeleitete Peptide sowie die Verwendung bestimmter, von den $g(a)1- oder $g(a)2-Domänen von HLA-B27 bzw. humanem Keratin VI abgeleiteter Peptide zur Diagnose und Behandlung von HLA-abhängigen Autoimmunerkrankungen.(EN) The invention concerns peptides derived from the $g(a)1 or $g(a)2 domains of HLA-B27 or human keratin IV as well as the use of specific peptides derived from the $g(a)1 or $g(a)2 domains of HLA-B27 or human keratin IV for diagnosing and treating HLA-dependent autoimmune diseases.(FR) L'invention concerne des peptides dérivés des domaines $g(a)1 ou $g(a)2 de HLA-B27 ou de kératine VI humaine, ainsi que l'utilisation de certains peptides dérivés des domaines $g(a)1 ou $g(a)2 de HLA-B27 ou de kératine VI humaine pour le diagnostic et le traitement de maladies auto-immunes dépendant de HLA.

  中文文本： (德语)这项发明涉及由 $g(a)1-或 $g(a)2- domaine von HLA-B27 bzw. wasserмäßigen Keratin VI abgeleitete Peptide und die Benutzung bestimmter, durch $g(a)1- oder $g(a)2- domaine von HLA-B27 bzw. wasserмäßigen Keratin VI abgeleitete Peptide zur Diagnose und Behandlung von HLA-abhängigen Autoimmunerkrankungen. (英语) The invention concerns peptides derived from the $g(a)1 or $g(a)2 domains of HLA-B27 or human keratin IV as well as the use of specific peptides derived from the $g(a)1 or $g(a)2 domains of HLA-B27 or human keratin IV for diagnosing and treating HLA-dependent autoimmune diseases. (法语) L'invention concerne des peptides dérivés des domaines $g(a)1 ou $g(a)2 de HLA-B27 ou de kératine VI humaine, ainsi que l'utilisation de certains peptides dérivés des domaines $g(a)1 ou $g(a)2 de HLA-B27 ou de kératine VI humaine pour le diagnostic et le traitement de maladies auto-immunes dépendant de HLA.
• Group 13 metal carbochalcogenoato complexes: Synthesis, X-ray structure analysis, and reactions
  作者：Norio Nakata、Shinzi Kato、Osamu Niyomura、Masahiro Ebihara

  DOI：10.1002/hc.21445

  日期：2018.12

  AbstractA series of alkali metal tetrakis(carbochalcogenoato)‐gallates and ‐indates M[M′(EOCR)4](solv.) (M = alkali metal; M′ = Ga, In; E = S, Se) and tris(carbodithioato)aluminum, ‐gallates and ‐indates M′ (SSCR)3 (M′ = Al, Ga, In) were prepared by the reactions of alkali metal carbochalcogenate with metal trihalogenides (M′X3; M′ = Al, Ga, In; X = Cl, Br) and by those of piperidinium carbodithioates or carbodithioic and carboselenoic acids with M′X3, respectively. An X‐ray molecular structure analysis revealed that they have an acetone molecule as a crystal solvent. The reactions of the potassium complexes K[M′ (EOCR)4](H2O) (E = S, Se) with methanol and primary and secondary amines gave the corresponding methyl ester and amides in good yields, while the reactions with iodomethane and iodine gave S‐ and Se‐methyl chalcogenoesters RCOEMe (E = S, Se) in good yields. Similar reactions of the tris(carbodithioato)gallates and ‐indates led to the corresponding O‐methyl thioesters, thioamides, and S‐methyl dithioesters in moderate to good yields. Oxidation of the tetrakis‐ and tris‐derivatives with iodine afforded the corresponding diacyl dichalcogenides (RCOE)2 (E = S, Se) and di(carbothioyl) disulfides in quantitative yields. These reactions appeared to occur on the carbonyl or selenium atom of the tetrakis compounds and on the sulfide sulfur or thiocarbonyl carbon atom of the tris‐compounds, respectively. A possible mechanism for these I2‐oxidation reactions is discussed.
• Mayer,R.; Scheithauer,S., Chemische Berichte, 1965, vol. 98, p. 829 - 837
  作者：Mayer,R.、Scheithauer,S.

  DOI：——

  日期：——
• Wuyts, Bulletin des Societes Chimiques Belges, 1930, vol. 39, p. 58,63
  作者：Wuyts

  DOI：——

  日期：——