2,6-Bis(3-bromo-4-hydroxybenzylidene)cyclohexanone

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二芳基庚烷
• 英文名称: 2,6-Bis(3-bromo-4-hydroxybenzylidene)cyclohexanone
• 英文别名: (2Z,6Z)-2,6-bis[(3-bromo-4-hydroxyphenyl)methylidene]cyclohexan-1-one
• 化学式: C₂₀H₁₆Br₂O₃
• 分子量: 464.1
• InChiKey: YOLKEKNTCBWPSD-SFGFDRCGSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  25
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• METHOD FOR OBTAINING PANCREATIC BETA CELL SURROGATES BY INCREASING PANCREATIC AND DUODENAL HOMEOBOX 1 (PDX-1) EXPRESSION
  申请人：Fundación Pública Andaluza Progreso Y Salud

  公开号：EP3191583A1

  公开（公告）日：2017-07-19
• HEMATOPOIETIC STEM AND PROGENITOR CELL EXPANSION SYSTEM
  申请人：Life Technologies Corporation

  公开号：EP3863648A1

  公开（公告）日：2021-08-18
• Hematopoietic Stem and Progenitor Cell Expansion System
  申请人：LIFE TECHNOLOGIES CORPORATION

  公开号：US20210386787A1

  公开（公告）日：2021-12-16

  Described herein is a growth medium for culture of stem cells and/or primary cells, in particular hematopoietic stem cells (HSCs), the growth medium including a basal medium and a supplement, with the medium and/or supplement including a histone acetyltransferase (HAT) inhibitor, a histone deacetylase (HDAC) inhibitor, and two or more of a lipid, an amino acid or amino acid derivative, an antioxidative agent, and an inorganic salt. Further provided are methods of using the growth medium, as well as kits and formulations of the growth medium.
• [EN] METHOD FOR OBTAINING PANCREATIC BETA CELL SURROGATES BY INCREASING PANCREATIC AND DUODENAL HOMEOBOX 1 (PDX-1) EXPRESSION<br/>[FR] PROCÉDÉ PERMETTANT D'OBTENIR DES SUBSTITUTS DE CELLULES BÊTA DU PANCRÉAS GRÂCE À UNE AUGMENTATION DE L'EXPRESSION DE PDX-1
  申请人：FUNDACION PUBLICA ANDALUZA PROGRESO Y SALUD

  公开号：WO2016038038A1

  公开（公告）日：2016-03-17

  Insulin producing cells capable of secreting blood glucose regulating hormones, specially insulin, in response to physiological signals, method of production of said cells and uses thereof.