Benzotriazole sulfide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并三唑类
• 英文名称: Benzotriazole sulfide
• 英文别名: 1-sulfanylbenzotriazole
• 化学式: C₆H₅N₃S
• 分子量: 151.19
• InChiKey: QEQMGPQHHWLTHV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  31.7
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• [EN] NOVEL COMPOUNDS SUITABLE FOR THE TREATMENT OF DYSLIPIDEMIA<br/>[FR] NOUVEAUX COMPOSÉS APPROPRIÉS POUR LE TRAITEMENT DE LA DYSLIPIDÉMIE
  申请人：CADILA HEALTHCARE LTD

  公开号：WO2014192023A1

  公开（公告）日：2014-12-04

  The present invention relates to compounds of the general formula (I), their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods for their preparation, use of these compounds in medicine and the intermediates involved in their preparation. The compounds of the present invention can be used to treat diseases such as hyperlipidemia and also have a beneficial effect on cholesterol.

  本发明涉及具有通用公式(I)的化合物、它们的互变异构体、它们的立体异构体、它们的药物可接受的盐、含有它们的药物组合物、它们的制备方法、在医学中使用这些化合物以及参与它们制备的中间体。本发明的化合物可以用于治疗诸如高脂血症之类的疾病，并且对胆固醇也有有益效果。
• HETEROCYCLIC COMPOUNDS SUITABLE FOR THE TREATMENT OF DYSLIPIDEMIA
  申请人：Pingali Harikishore

  公开号：US20130281366A1

  公开（公告）日：2013-10-24

  The present invention relates to compounds of the general formula (I), their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods for their preparation, use of these compounds in medicine and the intermediates involved in their preparation. The present invention is directed towards compounds which can be used to treat diseases such as Hyperlipidemia and also have a beneficial effect on cholesterol.

  本发明涉及一般式（I）的化合物，它们的互变异构体、立体异构体、药学上可接受的盐、含有它们的药物组合物、其制备方法、这些化合物在医学上的应用以及其制备中涉及的中间体。 本发明针对可用于治疗高脂血症等疾病并对胆固醇产生有益影响的化合物。
• [EN] COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND OTHER DISEASES<br/>[FR] COMPOSÉS POUR LE TRAITEMENT DE LA DYSLIPIDÉMIE ET D'AUTRES MALADIES
  申请人：CADILA HEALTHCARE LTD

  公开号：WO2014002105A1

  公开（公告）日：2014-01-03

  The present invention relates to compounds of the general formula (I), their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods for their preparation, use of these compounds in medicine and the intermediates involved in their preparation. The present invention is directed towards compounds which can be used to treat diseases such as hyperlipidemia and also have a beneficial effect on cholesterol.

  本发明涉及一般式（I）的化合物，它们的互变异构体，立体异构体，药学上可接受的盐，含有它们的药物组合物，它们的制备方法，这些化合物在医学上的应用以及其制备中涉及的中间体。本发明针对可用于治疗高脂血症等疾病并对胆固醇产生有益影响的化合物。
• [EN] NOVEL COMPOUNDS FOR THE TREATMENT OF DYSLIPIDEMIA AND RELATED DISEASES<br/>[FR] NOUVEAUX COMPOSÉS POUR LE TRAITEMENT DE LA DYSLIPIDÉMIE ET DE MALADIES ASSOCIÉES
  申请人：CADILA HEALTHCARE LTD

  公开号：WO2014002106A1

  公开（公告）日：2014-01-03

  The present invention relates to compounds of the general formula (I), their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods for their preparation, use of these compounds in medicine and the intermediates involved in their preparation. The present invention is directed to compounds suitable for the treatment of Disease conditions such as hyperlipidemia. The compounds of the present invention also lower LDL-c.

  本发明涉及一般式（I）的化合物，它们的互变异构体，立体异构体，药学上可接受的盐，含有它们的药物组合物，它们的制备方法，这些化合物在医学中的应用以及其制备中涉及的中间体。本发明涉及适用于治疗高脂血症等疾病状况的化合物。本发明的化合物还能降低LDL-c。
• Hydrosilylation Reaction Catalysts and Curable Compositions and Methods for Their Preparation and Use
  申请人：Dow Corning Corporation

  公开号：US20140296468A1

  公开（公告）日：2014-10-02

  A composition contains (A) a hydrosilylation reaction catalyst and (B) an aliphatically unsaturated compound having an average, per molecule, of one or more aliphatically unsaturated organic groups capable of undergoing hydrosilylation reaction. The composition is capable of reacting via hydrosilylation reaction to form a reaction product, such as a silane, a gum, a gel, a rubber, or a resin. Ingredient (A) contains an iron-organosilicon ligand complex that can be prepared by reacting an iron carbonyl compound and an organosilicon ligand.

  一种组合物包含（A）一个氢硅烷基化反应催化剂和（B）一种脂肪族不饱和化合物，每个分子平均含有一个或多个能够进行氢硅烷基化反应的脂肪族不饱和有机基团。该组合物能够通过氢硅烷基化反应反应形成反应产物，如硅烷、树脂、凝胶、橡胶或树脂。成分（A）包含一种铁-有机硅配体络合物，可通过反应铁羰基化合物和有机硅配体制备。