2,6-Cl2C6H3CHN(CH2)3NMe | 647824-35-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,6-Cl2C6H3CHN(CH2)3NMe
• 英文别名: 3-[(2,6-dichlorophenyl)methylideneamino]-N,N-dimethylpropan-1-amine
• CAS: 647824-35-9
• 化学式: C₁₂H₁₆Cl₂N₂
• 分子量: 259.178
• InChiKey: XZYAUEHGTZLNMC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  16
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  15.6
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,6-Cl2C6H3CHN(CH2)3NMe 以 丙酮 为溶剂， 生成 [Pt(N-(2-chlorobenzylidene)-N',N'-dimethyl-1,3-propanediamine(-1H))(1,2-bis(diphenylphosphino)ethane)]Cl
  参考文献：
  名称：

  Synthesis and reactivity of cyclometallated platinum (II) compounds containing [C,N,N′] terdentate ligands: Crystal structures of [PtCl{(CH3)2N(CH2)3NCH(4-ClC 6H3)}], [PtCl{(CH3)2N(CH2)3NCH(2-ClC6H3)}] and [PtCl{(CH3)2N(CH2)3NCH(3-(CH3)C6H3)}]

  摘要：

  The reaction of compound CiS-[PtCl2(dmos)(2)] With ligands RCHN(CH2)(3)NMe2 (1a-1h) in which R is a phenyl group containing substituents such as Cl, F, Me, NO2 and MeO produced compounds [PtCl2{(CH3)(2)N(CH2)(3)NCHR}] (2), as mixtures of Z and E isomers. When treated with an equimolar amount of sodium acetate in refluxing methanol compounds 2 gave cyclometallated platinum compounds 3 containing a terdentate [C,N,N'] ligand. The obtained compounds were fully characterized including structure determinations for compounds 3a, 3b and 3e. The effects of the substituents in the regioselectivity of the cyclometallation reaction and the reactivity of 3a and 3b with mono and bidentate phosphines were also studied. (c) 2005 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2005.06.038

文献信息

• Synthesis and reactivity of cyclometallated platinum (II) compounds containing [C,N,N′] terdentate ligands: Crystal structures of [PtCl{(CH3)2N(CH2)3NCH(4-ClC 6H3)}], [PtCl{(CH3)2N(CH2)3NCH(2-ClC6H3)}] and [PtCl{(CH3)2N(CH2)3NCH(3-(CH3)C6H3)}]
  作者：Alejandro Capapé、Margarita Crespo、Jaume Granell、Mercè Font-Bardía、Xavier Solans

  DOI：10.1016/j.jorganchem.2005.06.038

  日期：2005.10

  The reaction of compound CiS-[PtCl2(dmos)(2)] With ligands RCHN(CH2)(3)NMe2 (1a-1h) in which R is a phenyl group containing substituents such as Cl, F, Me, NO2 and MeO produced compounds [PtCl2(CH3)(2)N(CH2)(3)NCHR}] (2), as mixtures of Z and E isomers. When treated with an equimolar amount of sodium acetate in refluxing methanol compounds 2 gave cyclometallated platinum compounds 3 containing a terdentate [C,N,N'] ligand. The obtained compounds were fully characterized including structure determinations for compounds 3a, 3b and 3e. The effects of the substituents in the regioselectivity of the cyclometallation reaction and the reactivity of 3a and 3b with mono and bidentate phosphines were also studied. (c) 2005 Elsevier B.V. All rights reserved.