m-xylylene bis-acetamide | 131711-99-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: m-xylylene bis-acetamide
• 英文别名: m-xylylenediamide；N,N'-m-xylylene-bis-acetamide；α.α'-Bis-acetamino-m-xylol；N,N'-m-Xylylen-bis-acetamid；N.N'-Diacetyl-m-xylylendiamin；1,3-Bis(acetylaminomethyl)benzene；N-[[3-(acetamidomethyl)phenyl]methyl]acetamide
• CAS: 131711-99-4
• 化学式: C₁₂H₁₆N₂O₂
• mdl: MFCD03400825
• 分子量: 220.271
• InChiKey: ZRSLEYDYXGOJEI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  16
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  58.2
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  m-xylylene bis-acetamide 在 lithium aluminium tetrahydride 作用下， 以 四氢呋喃 为溶剂， 反应 48.0h， 以46%的产率得到1,3-Bis-ethylaminomethyl-benzol
  参考文献：
  名称：

  Synthesis of Water-soluble Diaza-1,2,5-thiadiazolocyclophanes

  摘要：

  DOI：

  10.3987/com-97-s71
• 作为产物：
  描述：

  间苯二甲胺 、 乙酰氯 在 sodium hydroxide 作用下， 反应 3.0h， 以52%的产率得到m-xylylene bis-acetamide
  参考文献：
  名称：

  Synthesis of Water-soluble Diaza-1,2,5-thiadiazolocyclophanes

  摘要：

  DOI：

  10.3987/com-97-s71

文献信息

• Amide exchange reaction: a simple and efficient CuO catalyst for diacetamide synthesis
  作者：Qinghe Li、Peixue Wang、Youquan Deng

  DOI：10.1039/c6ra05563j

  日期：——

  A highly copper-catalysed amide exchange reaction of hexamethylenediamine (HDA) with CH3CN and H2O for the synthesis of hexamethylenebisacetamide (HMBA) without an organic solvent or gas protection was developed. 100% HDA conversion and >99% HMBA selectivity was obtained. X-ray diffraction, scanning emission microscopy, and temperature-programmed reduction of hydrogen were used to characterize the

  开发了一种高度铜催化的六亚甲基二胺（HDA）与CH 3 CN和H 2 O的酰胺交换反应，无需有机溶剂或气体保护即可合成六亚甲基双乙酰胺（HMBA）。获得了100％的HDA转化率和> 99％的HMBA选择性。X射线衍射，扫描电子显微镜和程序升温还原氢气被用来表征催化剂的结构特性。还研究了反应机理。
• Antifouling material using hydroxyl group-containing acrylamide derivative and use thereof
  申请人：OKAZAKI Kouju

  公开号：US20080305292A1

  公开（公告）日：2008-12-11

  An antifouling material and an antifouling film, which are excellent in hydrophilicity and have such a characteristic that the surface is self-cleaned with rain water or the like, or can be easily cleaned up even when a contaminant adheres to the surface thereof, can be obtained by copolymerizing a composition containing an acrylamide derivative having at least one hydroxyl group in the molecule and a compound having at least two (meth)acryloyloxy groups in the molecule.

  一种防污材料和防污膜，具有极佳的亲水性，并具有这样的特性，即表面可以通过雨水等自我清洁，或者即使污染物附着在其表面上，也可以轻松清洁，通过共聚合含有至少一个羟基的丙烯酰胺衍生物和在分子中具有至少两个（甲基）丙烯酰氧基团的化合物的组合物可以获得该防污材料和防污膜。
• Organic Compounds
  申请人：Collingwood Stephen Paul

  公开号：US20080312217A1

  公开（公告）日：2008-12-18

  A Compound of formula (I) or tautomers, or stereoisomers, or solvates, or pharmaceutically acceptable salts thereof, wherein M 1 , M 1 , L 1 , L 2 , W 1 , W 2 , X 1 , X 2 , Y 1 , Y 2 , A, R 5 , and R 5a are as defined herein for the treatment of conditions mediated by the blockade of an epithelial sodium channel, particularly an inflammatory or allergic condition.

  化合物式（I）或其互变异构体、立体异构体、溶剂化物或药学上可接受的盐，其中M1、M1、L1、L2、W1、W2、X1、X2、Y1、Y2、A、R5和R5a的定义如本文所述，用于治疗由于阻断上皮钠通道介导的情况，特别是炎症或过敏症。
• METHOD FOR PRODUCING CARBAMATE COMPOUND
  申请人：Ube Industries, Ltd.

  公开号：EP2325167A1

  公开（公告）日：2011-05-25

  A task of the present invention is to provide a process for preparation a carbamate compound using a carbonic acid ester and an amide compound in the presence of a basic compound(s), wherein the process is a novel industrial method which is advantageous in that the reaction rate is faster than conventional and the by-produced ester compound can be recovered, and the present invention is directed to a method comprising reacting an amide compound represented by the formula (1) with a carbonic acid ester represented by the formula (2) in the presence of a basic compound(s) to obtain a carbamate compound represented by the formula (3).

  本发明的任务是提供一种在碱性化合物存在下使用碳酸酯和酰胺化合物制备氨基甲酸 酯化合物的工艺，其中该工艺是一种新颖的工业方法，其优点是反应速率比传统方法快， 且副生成的酯化合物可以回收、本发明涉及一种方法，包括在碱性化合物存在下，使式（1）代表的酰胺化合物与式（2）代表的碳酸酯反应，得到式（3）代表的氨基甲酸酯化合物。
• Oxygen scavenging compositions, articles containing same, and methods of their use
  申请人：Plastipak Packaging, Inc.

  公开号：US11338983B2

  公开（公告）日：2022-05-24

  The disclosure relates to oxygen scavenging compositions, methods of making the compositions, articles prepared from the compositions, and methods of making the articles. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

  本发明涉及氧清除组合物、组合物的制造方法、由组合物制备的物品以及物品的制造方法。本摘要旨在作为在特定技术领域进行搜索的扫描工具，并非对本发明的限制。