Di-tert-butyl-hex-1-ynyl-silane | 321674-11-7

• 分子结构分类: 有机化合物 - 碳氢化合物衍生物
• 英文名称: Di-tert-butyl-hex-1-ynyl-silane
• 英文别名: Ditert-butyl(hex-1-ynyl)silane；ditert-butyl(hex-1-ynyl)silane
• CAS: 321674-11-7
• 化学式: C₁₄H₂₈Si
• 分子量: 224.462
• InChiKey: LAJYZRWITFXAJE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.55
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  Di-tert-butyl-hex-1-ynyl-silane 在 N-溴代丁二酰亚胺(NBS) 作用下， 以 四氯化碳 为溶剂， 反应 1.5h， 以100%的产率得到Bromo-di-tert-butyl-hex-1-ynyl-silane
  参考文献：
  名称：

  Synthesis of cyclic allenylsilanes via an intramolecular substitution reaction of 1-siloxy-2,3-epoxyalkanes

  摘要：

  Intramolecular substitution reactions of 1-(alkynylsiloxy)-2,3-epoxyalkanes under acidic or basic conditions were investigated. In the presence of t-butyllithium, cyclic allenylsilanes, which can be easily converted to the corresponding allenes, were obtained in good yields. The regioselectivity was highly dependent on the configuration of the epoxide moiety, which was rationalized by assuming chair-like transition state models of the 6-endo type cyclization reactions. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(00)01699-3
• 作为产物：
  描述：

  di-tert-butylchlorosilane 、 1-hexynyllithium 在 六甲基磷酰三胺 作用下， 以 乙醚 为溶剂， 反应 0.5h， 以84%的产率得到Di-tert-butyl-hex-1-ynyl-silane
  参考文献：
  名称：

  Synthesis of cyclic allenylsilanes via an intramolecular substitution reaction of 1-siloxy-2,3-epoxyalkanes

  摘要：

  Intramolecular substitution reactions of 1-(alkynylsiloxy)-2,3-epoxyalkanes under acidic or basic conditions were investigated. In the presence of t-butyllithium, cyclic allenylsilanes, which can be easily converted to the corresponding allenes, were obtained in good yields. The regioselectivity was highly dependent on the configuration of the epoxide moiety, which was rationalized by assuming chair-like transition state models of the 6-endo type cyclization reactions. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(00)01699-3